Fig. 2From: Concept mapping One-Carbon Metabolism to model future ontologies for nutrient–gene–phenotype interactionsOCM plus upstream and downstream pathway integration. One-Carbon Metabolism relies on many closely related pathways for substrate and cofactor production. A few of the important pathways are visualized here. OCM is also important for providing cofactors and substrates for a multitude of subsequent reactions ranging from epigenetic methylation of genes to purine productionBack to article page