TY - JOUR AU - Beaudoin, M. S. AU - Robinson, L. E. AU - Graham, T. E. PY - 2011 DA - 2011// TI - An oral lipid challenge and acute intake of caffeinated coffee additively decrease glucose tolerance in healthy men JO - J Nutr VL - 141 UR - https://doi.org/10.3945/jn.110.132761 DO - 10.3945/jn.110.132761 ID - Beaudoin2011 ER - TY - JOUR AU - Blaak, E. E. AU - Hul, G. AU - Verdich, C. AU - Stich, V. AU - Martinez, A. AU - Petersen, M. AU - Feskens, E. F. M. PY - 2006 DA - 2006// TI - Fat oxidation before and after a high fat load in the obese insulin-resistant state JO - J Clin Endocrinol Metab VL - 91 UR - https://doi.org/10.1210/jc.2005-1598 DO - 10.1210/jc.2005-1598 ID - Blaak2006 ER - TY - JOUR AU - Blaak, E. E. AU - Antoine, J. -. M. AU - Benton, D. AU - Björck, I. AU - Bozzetto, L. AU - Brouns, F. AU - Diamant, M. PY - 2012 DA - 2012// TI - Impact of postprandial glycaemia on health and prevention of disease JO - Obes Rev VL - 13 UR - https://doi.org/10.1111/j.1467-789X.2012.01011.x DO - 10.1111/j.1467-789X.2012.01011.x ID - Blaak2012 ER - TY - STD TI - Bondia-Pons I, Maukonen J, Mattila I, Rissanen A, Saarela M, Kaprio J, Hakkarainen A et al (2014) Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a big mac challenge. FASEB J, 1–11. doi:10.1096/fj.14-250167 ID - ref4 ER - TY - JOUR AU - Bosch, J. P. AU - Lauer, A. AU - Glabman, S. PY - 1984 DA - 1984// TI - Short-term protein loading in assessment of patients with renal disease JO - Am J Med VL - 77 UR - https://doi.org/10.1016/0002-9343(84)90529-1 DO - 10.1016/0002-9343(84)90529-1 ID - Bosch1984 ER - TY - JOUR AU - Chan, D. C. AU - Pang, J. AU - Romic, G. AU - Watts, G. F. PY - 2013 DA - 2013// TI - Postprandial hypertriglyceridemia and cardiovascular disease: current and future therapies JO - Curr Atheroscler Rep VL - 15 UR - https://doi.org/10.1007/s11883-013-0309-9 DO - 10.1007/s11883-013-0309-9 ID - Chan2013 ER - TY - JOUR AU - Dallmann, R. AU - Viola, A. U. AU - Tarokh, L. AU - Cajochen, C. AU - Brown, S. A. PY - 2012 DA - 2012// TI - The human circadian metabolome JO - Proc Natl Acad Sci USA VL - 109 UR - https://doi.org/10.1073/pnas.1114410109 DO - 10.1073/pnas.1114410109 ID - Dallmann2012 ER - TY - STD TI - De Wit NJW, Afman LA, Mensink M, Müller M (2012) Phenotyping the effect of diet on non-alcoholic fatty liver disease. J Hepatol xxx (6). European Association for the Study of the Liver: 1370–73. doi:10.1016/j.jhep.2012.07.003 ID - ref8 ER - TY - JOUR AU - Derosa, G. AU - Ferrari, I. AU - D’Angelo, A. AU - Salvadeo, S. A. T. AU - Fogari, E. AU - Gravina, A. AU - Mereu, R. PY - 2009 DA - 2009// TI - Oral fat load effects on inflammation and endothelial stress markers in healthy subjects JO - Heart Vess VL - 24 UR - https://doi.org/10.1007/s00380-008-1109-y DO - 10.1007/s00380-008-1109-y ID - Derosa2009 ER - TY - JOUR AU - Derosa, G. AU - D’Angelo, A. AU - Salvadeo, S. A. T. AU - Ferrari, I. AU - Fogari, E. AU - Gravina, A. AU - Mereu, R. PY - 2010 DA - 2010// TI - Oral glucose tolerance test effects on endothelial inflammation markers in healthy subjects and diabetic patients JO - Horm Metab Res VL - 42 UR - https://doi.org/10.1055/s-0029-1237728 DO - 10.1055/s-0029-1237728 ID - Derosa2010 ER - TY - STD TI - Eckel-Mahan KL, Patel VR, Mohney RP, Vignola KS, Baldi P, Sassone-Corsi P (2012) Coordination of the transcriptome and metabolome by the circadian clock. Proc Natl Acad Sci USA. doi:10.1073/pnas.1118726109 ID - ref11 ER - TY - JOUR AU - Felig, P. AU - Marliss, E. AU - Cahill, G. F. PY - 1969 DA - 1969// TI - Plasma amino acid levels and insulin secretion in obesity JO - N Eng J Med VL - 281 UR - https://doi.org/10.1056/NEJM196910092811503 DO - 10.1056/NEJM196910092811503 ID - Felig1969 ER - TY - JOUR AU - Fernandes, J. AU - Kamer, J. H. PY - 1968 DA - 1968// TI - Hexose and protein tolerance tests in children with liver glycogenosis caused by a deficiency of the debranching enzyme system JO - Pediatrics VL - 41 ID - Fernandes1968 ER - TY - JOUR AU - Fielding, B. PY - 2011 DA - 2011// TI - Tracing the fate of dietary fatty acids: metabolic studies of postprandial lipaemia in human subjects JO - Proc Nutr Soc VL - 70 UR - https://doi.org/10.1017/S002966511100084X DO - 10.1017/S002966511100084X ID - Fielding2011 ER - TY - JOUR AU - Fischer, L. M. AU - Costa, K. A. AU - Galanko, J. AU - Sha, W. AU - Stephenson, B. AU - Vick, J. AU - Zeisel, S. H. PY - 2010 DA - 2010// TI - Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma JO - Am J Clin Nutr VL - 92 UR - https://doi.org/10.3945/ajcn.2010.29459 DO - 10.3945/ajcn.2010.29459 ID - Fischer2010 ER - TY - JOUR AU - Fujioka, Y. AU - Ishikawa, Y. PY - 2009 DA - 2009// TI - Remnant lipoproteins as strong key particles to atherogenesis JO - J Atheroscler Thromb VL - 16 UR - https://doi.org/10.5551/jat.E598 DO - 10.5551/jat.E598 ID - Fujioka2009 ER - TY - STD TI - Geneontology. http://amigo.geneontology.org/ UR - http://amigo.geneontology.org/ ID - ref17 ER - TY - JOUR AU - Ho, J. E. AU - Larson, M. G. AU - Vasan, R. S. AU - Ghorbani, A. AU - Cheng, S. AU - Rhee, E. P. AU - Florez, J. C. AU - Clish, C. B. AU - Gerszten, R. E. AU - Wang, T. J. PY - 2013 DA - 2013// TI - Metabolite profiles during oral glucose challenge JO - Diabetes VL - 62 UR - https://doi.org/10.2337/db12-0754 DO - 10.2337/db12-0754 ID - Ho2013 ER - TY - JOUR AU - Hoang, H. H. AU - Padgham, S. V. AU - Meininger, C. J. PY - 2013 DA - 2013// TI - l-Arginine, tetrahydrobiopterin, nitric oxide and diabetes JO - Curr Opin Clin Nutr Metab Care VL - 16 UR - https://doi.org/10.1097/MCO.0b013e32835ad1ef DO - 10.1097/MCO.0b013e32835ad1ef ID - Hoang2013 ER - TY - JOUR AU - Jones, A. AU - McMillan, M. R. AU - Jones, R. W. AU - Kowalik, G. T. AU - Steeden, J. A. AU - Deanfield, J. E. AU - Pruessner, J. C. AU - Taylor, A. M. AU - Muthurangu, V. PY - 2012 DA - 2012// TI - Adiposity is associated with blunted cardiovascular, neuroendocrine and cognitive responses to acute mental stress JO - PloS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0039143 DO - 10.1371/journal.pone.0039143 ID - Jones2012 ER - TY - JOUR AU - Kaore, S. N. AU - Amane, H. S. AU - Kaore, N. M. PY - 2013 DA - 2013// TI - Citrulline: pharmacological perspectives and its role as an emerging biomarker in future JO - Fundam Clin Pharmacol VL - 27 UR - https://doi.org/10.1111/j.1472-8206.2012.01059.x DO - 10.1111/j.1472-8206.2012.01059.x ID - Kaore2013 ER - TY - STD TI - Krug S, Kastenmüller G, Stückler F, Rist MJ, Skurk T, Sailer M, Raffler J, et al (2012) The dynamic range of the human metabolome revealed by challenges. FASEB J. doi:10.1096/fj.11-198093 ID - ref22 ER - TY - STD TI - Laus MF, Duarte Manhas Ferreira Vales L, Braga Costa TM, Sousa Almeida S (2011) Early postnatal protein-calorie malnutrition and cognition: a review of human and animal studies. Int J Environ Res Public Health 8(2):590–612. doi:10.3390/ijerph8020590 ID - ref23 ER - TY - STD TI - Lawton KA, Berger A, Mitchell M, Milgram KE, Evans AM, Guo L, Hanson RW, Kalhan SC, Ryals JA, Milburn MV (2008) Analysis of the adult human plasma metabolome. Pharmacogenomics 9 (1744-8042 (Electronic) LA–eng PT–Comparative Study PT–Journal Article SB–IM). Metabolon, Inc, 800 Capitola Dr. Suite 1, Durham, NC 27713, USA: 383–97. PM:18384253 ID - ref24 ER - TY - STD TI - Liang W, Lindeman JH, Menke AL, Koonen DP, Morrison M, Havekes LM, van den Hoek AM, Kleemann R (2014) Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation. Lab Invest 94(5). Nature Publishing Group: 491–502. doi:10.1038/labinvest.2014.11 ID - ref25 ER - TY - JOUR AU - Lichtenstein, L. AU - Mattijssen, F. AU - Wit, N. J. AU - Georgiadi, A. AU - Hooiveld, G. J. AU - Meer, R. AU - He, Y. PY - 2010 DA - 2010// TI - Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages JO - Cell Metab VL - 12 UR - https://doi.org/10.1016/j.cmet.2010.11.002 DO - 10.1016/j.cmet.2010.11.002 ID - Lichtenstein2010 ER - TY - JOUR AU - Lusis, A. J. AU - Attie, A. D. AU - Reue, K. PY - 2008 DA - 2008// TI - Metabolic syndrome: from epidemiology to systems biology JO - Nat Rev Genet VL - 9 UR - https://doi.org/10.1038/nrg2468 DO - 10.1038/nrg2468 ID - Lusis2008 ER - TY - JOUR AU - Malaguarnera, M. AU - Gargante, M. P. AU - Russo, C. AU - Antic, T. AU - Vacante, M. AU - Malaguarnera, M. AU - Avitabile, T. AU - Volti, G. L. AU - Galvano, F. PY - 2010 DA - 2010// TI - L-Carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis: a randomized and controlled clinical trial JO - Am J Gastroenterol VL - 105 UR - https://doi.org/10.1038/ajg.2009.719 DO - 10.1038/ajg.2009.719 ID - Malaguarnera2010 ER - TY - JOUR AU - McCormack, S. E. AU - McCarthy, M. A. AU - Harrington, S. G. AU - Farilla, L. AU - Hrovat, M. I. AU - Systrom, D. M. AU - Thomas, B. J. PY - 2013 DA - 2013// TI - Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents JO - Pediatr Obes ID - McCormack2013 ER - TY - STD TI - Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, et al (2007) PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. PLoS.Genet 3(1553–7404 (Electronic) LA–eng PT–Comparative Study PT–Journal Article PT–Research Support, Non-U.S. Gov’t RN–0 (Lipids) RN–0 (PPAR gamma) RN–11061-68-0 (Insulin) SB–IM). Department of Clinical Biochemistry, Histopathology, University of Cambridge/Addenbrooke’s Hospital, Cambridge, United Kingdom: e64. PM:17465682 ID - ref30 ER - TY - JOUR AU - Menni, C. AU - Fauman, E. AU - Erte, I. AU - Perry, J. R. B. AU - Kastenmüller, G. AU - Shin, S. -. Y. AU - Petersen, A. -. K. PY - 2013 DA - 2013// TI - Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach JO - Diabetes VL - 62 UR - https://doi.org/10.2337/db13-0570 DO - 10.2337/db13-0570 ID - Menni2013 ER - TY - JOUR AU - Mihas, C. AU - Kolovou, G. D. AU - Mikhailidis, D. P. AU - Kovar, J. AU - Lairon, D. AU - Nordestgaard, B. G. AU - Chye Ooi, T. PY - 2011 DA - 2011// TI - Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis JO - Curr Vasc Pharmacol VL - 9 UR - https://doi.org/10.2174/157016111795495530 DO - 10.2174/157016111795495530 ID - Mihas2011 ER - TY - JOUR AU - Musso, G. AU - Gambino, R. AU - Pacini, G. AU - Michieli, F. AU - Cassader, M. PY - 2009 DA - 2009// TI - Prolonged saturated fat-induced, glucose-dependent insulinotropic polypeptide elevation is associated with adipokine imbalance and liver injury in nonalcoholic steatohepatitis: dysregulated enteroadipocyte axis as a novel feature of fatty liver JO - Am J Clin Nutr VL - 89 UR - https://doi.org/10.3945/ajcn.2008.26720 DO - 10.3945/ajcn.2008.26720 ID - Musso2009 ER - TY - STD TI - Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF, Haqq AM, et al (2009) A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 9(4). Elsevier Ltd: 311–326. doi:10.1016/j.cmet.2009.02.002 ID - ref34 ER - TY - JOUR AU - Noland, R. C. AU - Koves, T. R. AU - Seiler, S. E. AU - Lum, H. AU - Lust, R. M. AU - Ilkayeva, O. AU - Stevens, R. D. AU - Hegardt, F. G. AU - Muoio, D. M. PY - 2009 DA - 2009// TI - Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.032888 DO - 10.1074/jbc.M109.032888 ID - Noland2009 ER - TY - STD TI - Osborn O, Olefsky JM (2012) The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 18(3). Nature Publishing Group: 363–374. doi:10.1038/nm.2627 ID - ref36 ER - TY - STD TI - Pellis L, Erk MJ, Ommen B, Bakker GCM, Hendriks HFJ, Cnubben NHP, Kleemann R et al (2011) Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status. Metabolomics. doi:10.1007/s11306-011-0320-5 ID - ref37 ER - TY - JOUR AU - Phillips, C. M. AU - Goumidi, L. AU - Bertrais, S. AU - Ferguson, J. F. AU - Field, M. R. AU - Kelly, E. D. AU - Mehegan, J. PY - 2010 DA - 2010// TI - Additive effect of polymorphisms in the IL-6, LTA, and TNF-alpha genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components JO - J Clin Endocrinol Metab VL - 95 UR - https://doi.org/10.1210/jc.2009-1081 DO - 10.1210/jc.2009-1081 ID - Phillips2010 ER - TY - JOUR AU - Rutlegde, A. C. AU - Adeli, K. PY - 2007 DA - 2007// TI - Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms JO - Nutr Rev VL - 65 UR - https://doi.org/10.1301/nr.2007.jun.S13-S23 DO - 10.1301/nr.2007.jun.S13-S23 ID - Rutlegde2007 ER - TY - STD TI - Shaham O, Wei R, Wang TJ, Ricciardi C, Lewis GD, Vasan RS, Carr SA, Thadhani R, Gerszten RE, Mootha VK (2008) Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity. Mol Syst Biol 4(214). EMBO and Nature Publishing Group: 214. doi:10.1038/msb.2008.50 ID - ref40 ER - TY - JOUR AU - Spégel, P. AU - Danielsson, A. P. H. AU - Bacos, K. AU - Nagorny, C. L. F. AU - Moritz, T. AU - Mulder, H. AU - Filipsson, K. PY - 2009 DA - 2009// TI - Metabolomic analysis of a human oral glucose tolerance test reveals fatty acids as reliable indicators of regulated metabolism JO - Metabolomics VL - 6 UR - https://doi.org/10.1007/s11306-009-0177-z DO - 10.1007/s11306-009-0177-z ID - Spégel2009 ER - TY - JOUR AU - Steptoe, A. AU - Dockray, S. AU - Wardle, J. PY - 2009 DA - 2009// TI - Positive affect and psychobiological processes relevant to health JO - J Pers VL - 77 UR - https://doi.org/10.1111/j.1467-6494.2009.00599.x DO - 10.1111/j.1467-6494.2009.00599.x ID - Steptoe2009 ER - TY - JOUR AU - Dijk, S. J. AU - Mensink, M. AU - Esser, D. AU - Feskens, E. J. M. AU - Müller, M. AU - Afman, L. A. PY - 2012 DA - 2012// TI - Responses to high-fat challenges varying in fat type in subjects with different metabolic risk phenotypes: a randomized trial JO - PloS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0041388 DO - 10.1371/journal.pone.0041388 ID - Dijk2012 ER - TY - JOUR AU - Ommen, B. AU - Keijer, J. AU - Kleemann, R. AU - Elliott, R. AU - Drevon, C. A. AU - McArdle, H. AU - Gibney, M. AU - Müller, M. PY - 2008 DA - 2008// TI - The challenges for molecular nutrition research 2: quantification of the nutritional phenotype JO - Genes Nutr VL - 3 UR - https://doi.org/10.1007/s12263-008-0084-3 DO - 10.1007/s12263-008-0084-3 ID - Ommen2008 ER - TY - STD TI - Van Ommen B, Keijer J, Heil SG, Kaput J (2009) Challenging homeostasis to define biomarkers for nutrition related health. Mol Nutr Food Res 53(July). RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands. ben.vanommen@tno.nl: 795–804. PM:19517455 ID - ref45 ER - TY - STD TI - Vance DE (2013) Phospholipid methylation in mammals: from biochemistry to physiological function. Biochim Biophys Acta. doi:10.1016/j.bbamem.2013.10.018 ID - ref46 ER - TY - STD TI - Virtue S, Vidal-Puig A (2010) Adipose tissue expandability, lipotoxicity and the metabolic syndrome–an allostatic perspective. Biochim Biophys Acta 1801(3). Elsevier B.V. 338–49. doi:10.1016/j.bbalip.2009.12.006 ID - ref47 ER - TY - STD TI - Vis DJ, Westerhuis JA, Jacobs DM, van Duynhoven JPM, Wopereis S, van Ommen B, Hendriks MMWB, Smilde AK (2014) Analyzing metabolomics-based challenge tests. Metabolomics. doi:10.1007/s11306-014-0673-7 ID - ref48 ER - TY - STD TI - Wopereis S, Rubingh CM, van Erk MJ, Verheij ER, van Vliet T, Cnubben NHP, Smilde AK, van der Greef J, van Ommen B, Hendriks HFJ (2009) Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes. PLoS ONE 4(2). Public Library of Science: e4525. doi:10.1371/journal.pone.0004525 ID - ref49 ER - TY - JOUR AU - Wopereis, S. AU - Wolvers, D. AU - Erk, M. AU - Gribnau, M. AU - Kremer, B. AU - Dorsten, F. A. AU - Boelsma, E. PY - 2013 DA - 2013// TI - Assessment of inflammatory resilience in healthy subjects using dietary lipid and glucose challenges JO - BMC Med Genom VL - 6 UR - https://doi.org/10.1186/1755-8794-6-44 DO - 10.1186/1755-8794-6-44 ID - Wopereis2013 ER - TY - JOUR AU - Zhao, X. AU - Peter, A. AU - Fritsche, J. AU - Elcnerova, M. AU - Fritsche, A. AU - Häring, H. -. U. AU - Schleicher, E. D. AU - Xu, G. AU - Lehmann, R. PY - 2009 DA - 2009// TI - Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at? JO - Am J Physiol Endocrinol Metab VL - 296 UR - https://doi.org/10.1152/ajpendo.90748.2008 DO - 10.1152/ajpendo.90748.2008 ID - Zhao2009 ER -