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Table 2 MT1A +1245 A/G genotypic and allelic frequencies in elderly study subjects according to gender

From: Influence of +1245 A/G MT1A polymorphism on advanced glycation end-products (AGEs) in elderly: effect of zinc supplementation

 

Males

n = 57

Females

n = 53

All subjects

n = 110

Genotypes

1245 AA (Lys/Lys)

70.2 % (40)

83 % (44)

76.4 % (84)

1267 AG (Lys/Arg)

28 % (16)

17 % (9)

22.7 % (25)

1267 GG (Arg/Arg)

1.8 % (1)

0 % (0)

0.9 % (1)

Alleles

A allele

0.84

0.92

0.88

G allele

0.16

0.08

0.12

  1. Pearson χ 2 = 3.009, df = 2, p = 0.22 (genotypic frequency)
  2. Pearson χ 2 = 2.718, df = 1, p = 0.09 (allelic frequency)
  3. Lys Lysine, Arg Arginine