Table 3 Influence of +1245 MT1A A/G SNP on clinical and biochemical parameters
|  | G− genotype Baseline | G+ genotype Baseline | p value |
|---|---|---|---|
CRP (mg/dL) | 0.55 ± 1.46 | 0.42 ± 0.58 | 0.91 |
Albumin (g/dL) | 4.1 ± 0.2 | 4.0 ± 0.2 | 0.41 |
Glycemia (mg/dL) | 96.7 ± 13.8 | 96.1 ± 9.1 | 0.53 |
Total cholesterol (mg/dL) | 223.2 ± 41.8 | 219.2 ± 34.3 | 0.70 |
HDL-cholesterol (mg/dL) | 53.1 ± 14.2 | 49.2 ± 16.2 | 0.28 |
Triglycerides (mg/dL) | 122.1 ± 52.8 | 133.7 ± 72.5 | 0.24 |
AGEs (ng/mL) | 1.31 ± 0.50 | 1.66 ± 0.62 | 0.036 |
ROS (MFI) | 4.1 ± 2.1 | 24.0 ± 18.3 | 0.01 |
pSOD (U/mL) | 21.53 ± 2.85 | 21.18 ± 3.26 | 0.65 |
GPx (nmol NADPH/min/mL) | 0.100 ± 0.006 | 0.099 ± 0.006 | 0.37 |
CAT (μmol/min/mg prot) | 20.80 ± 2.67 | 21.40 ± 2.92 | 0.35 |
Zn plasma levels (μM) | 10.58 ± 2.21 | 11.12 ± 2.24 | 0.22 |
Zn granulocytes (nmol/mg protein) | 0.21 ± 0.12 | 0.20 ± 0.12 | 0.92 |
MT (MFI) | 87.52 ± 32.13 | 89.21 ± 38.78 | 0.88 |
iZnL | 1.27 ± 0.12 | 1.24 ± 0.09 | 0.44 |
iZnR | 0.18 ± 0.07 | 0.17 ± 0.06 | 0.47 |