Table 1 Baseline serum levels of total, LDL cholesterol and β-Cx according to NPC1L1 L272L and ABCG8 A632 V polymorphisms
Total cholesterol (mmol/l) | P* | c-LDL (mmol/l) | P* | c-HDL (mmol/l) | P* | β-Cx (µmol/l) | P* | |
|---|---|---|---|---|---|---|---|---|
Beverage containing plant sterols | ||||||||
NPC1L1 L272L | ||||||||
CC (n = 9; 47 %) | 5.74 (0.25) | 0.373 | 3.65 (0.24) | 0.740 | 1.60 (0.05) | 0.165 | 0.334 (0.065) | 0.273 |
CG/GG (n = 10; 52 %) | 6.03 (0.19) | 3.75 (0.20) | 1.81 (0.13) | 0.439 (0.065) | ||||
All (n = 19) | 5.89 (0.13) | 3.70 (0.15) | 1.76 (0.08) | 0.391 (0.047) | ||||
ABCG8 A632 V | ||||||||
CC (n = 14; 74 %) | 5.74 (0.19) | 0.205 | 3.59 (0.17) | 0.341 | 1.68 (0.06) | 0.284 | 0.372 (0.047) | 0.471 |
CT/TT (n = 5; 26 %) | 6.18 (0.13) | 3.93 (0.22) | 1.86 (0.24) | 0.449 (0.099) | ||||
All (n = 19) | 5.87 (0.13) | 3.67 (0.14) | 1.73 (0.07) | 0.393 (0.043) | ||||
Beverage containing plant sterols plus β-Cx | ||||||||
NPC1L1 L272L | ||||||||
CC (n = 9; 47 %) | 5.12 (0.31) | 0.710 | 3.88 (0.32) | 0.820 | 1.50 (0.05) | 0.026 | 0.297 (0.058) | 0.251 |
CG/GG (n = 10; 52 %) | 6.03 (0.26) | 3.77 (0.24) | 1.78 (0.09) | 0.402 (0.065) | ||||
All (n = 19) | 5.95 (0.20) | 3.83 (0.19) | 1.66 (0.06) | 0.351 (0.043) | ||||
ABCG8 A632 V | ||||||||
CC (n = 14; 74 %) | 5.69 (0.25) | 0.520 | 3.88 (0.32) | 0.610 | 1.60 (0.05) | 0.130 | 0.311 (0.054) | 0.240 |
CT/TT (n = 5; 26 %) | 6.13 (0.23) | 3.77 (0.24) | 1.81 (0.19) | 0.430 (0.052) | ||||
All (n = 19) | 5.92 (0.19) | 3.80 (0.18) | 1.66 (0.06) | 0.340 (0.052) | ||||