Table 2 Colorectal adenoma risk associated with dietary HAA intake and exposure to meat mutagenicity in the total study population and separately among females and males

PhIP

≤116.30

55/36

Referent

37/19

Referent

18/17

Referent

116.31–232.61

66/32

0.73 (0.37, 1.44)

43/8

0.44 (0.16, 1.20)

23/24

1.34 (0.52, 3.50)

232.62–348.91

39/18

0.60 (0.26, 1.35)

27/5

0.32 (0.10, 1.04)

12/13

1.27 (0.39, 4.10)

>348.92

53/37

0.99 (0.49, 1.97)

41/13

0.56 (0.23, 1.38)

12/24

2.14 (0.74, 6.51)

MeIQx

≤18.54

75/32

Referent

54/12

Referent

21/20

Referent

18.55–37.09

56/32

1.38 (0.68, 2.78)

38/13

1.94 (0.74, 5.07)

18/19

0.97 (0.36, 2.61)

37.10–55.63

29/26

2.18 (1.02, 4.68)

19/10

2.39 (0.81, 7.08)

10/16

2.02 (0.68, 5.94)

>55.64

53/33

1.25 (0.62, 2.50)

37/10

0.94 (0.34, 2.55)

16/23

1.67 (0.63, 4.51)

DiMeIQx

≤2.06

73/37

Referent

54/16

Referent

19/21

Referent

2.07–4.12

58/29

0.78 (0.39, 1.58)

38/10

0.79 (0.30, 2.08)

20/19

0.79 (0.30, 2.13)

4.13–6.18

29/22

1.24 (0.57, 2.71)

18/10

1.58 (0.56, 4.46)

11/12

0.97 (0.32, 2.98)

>6.19

53/35

1.17 (0.59, 2.30)

38/9

0.68 (0.26, 1.79)

15/26

1.98 (0.73, 5.37)

Meat mutagenicity

≤3,589.83

54/29

Referent

40/13

Referent

14/16

Referent

3,589.84–7,179.67

71/33

0.88 (0.44, 1.78)

47/14

0.96 (0.38, 2.44)

24/19

0.75 (0.31, 2.39)

7,179.68–10,769.50

35/26

0.98 (0.44, 2.15)

19/8

1.09 (0.36, 3.33)

16/18

1.01 (0.34, 2.98)

>10,769.51

53/35

1.17 (0.57, 2.42)

42/10

0.63 (0.23, 1.71)

11/25

2.58 (0.84, 7.94)