Table 1 Demographic, anthropometric, and serum biochemical parameters of non-insulin- and insulin-resistant subjects (n = 115)

Gender (F/M)

27/22

41/25

NS

Age (years)

41 ± 10

39 ± 11

NS

BMI (kg/m²)

29.8 ± 10.9

44.2 ± 11.8

<0.001

Body fat (%)

33.6 ± 11.2

48.7 ± 6.5

<0.001

Adipocyte area (µm²)

3061 (1,830–4,064)

4769 (2,871–5,256)

<0.005

Glucose (mmol/l)

4.9 ± 0.6

5.8 ± 0.9

<0.001

Insulin (pmol/l)

48.8 (34.4–64.6)

166.5 (109–202)

<0.001

HOMA-IR

1.6 ± 0.6

5.4 ± 3.2

<0.001

Triglycerides (mmol/l)

2.0 (1.2–2.5)

1.9 (1.4–2.4)

NS

Cholesterol (mmol/l)

4.9 ± 1.0

4.6 ± 0.8

NS

HDL (mmol/l)

1.1 ± 0.4

1.0 ± 0.3

NS

LDL (mmol/l)

2.8 ± 0.8

2.6 ± 0.6

NS

Apo A (mmol/l)

3.5 ± 0.9

3.4 ± 0.7

NS

Apo B (mmol/l)

2.6 ± 0.7

2.5 ± 0.6

NS

Adiponectin (mg/l)

9.6 ± 5.0

8.0 ± 2.3

NS

Leptin (mg/l)

21.1 (7.1–22.5)

69.4 (26.6–102.6)

<0.001

CRP (mg/l)

40 (10–59)

57 (33–83)

<0.005