Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

Table 1 Genes affected by the extended fast according to the criteria uncorrected p value <0.05 and magnitude of fold change >1.4 as determined using a linear model analysis also taking into account, gender, BMI and subject effects

Probeset ID	GeneName	Fold change	Adjusted p value
207113_s_at	TNF	−1.74	0.00002
202887_s_at	DDIT4	1.64	0.00002
203633_at	CPT1A	1.64	0.00003
203821_at	HBEGF	2.57	0.00005
225207_at	PDK4	2.26	0.00019
207850_at	CXCL3	−1.47	0.00025
201631_s_at	IER3	−1.95	0.00058
202284_s_at	CDKN1A	1.70	0.00060
223217_s_at	NFKBIZ	−1.57	0.00071
203658_at	SLC25A20	1.42	0.00077
207156_at	HIST1H2AG	1.49	0.00126
205239_at	AREG	2.31	0.00173
206283_s_at	TAL1	1.66	0.00198
205114_s_at	CCL3	−2.11	0.00220
224856_at	FKBP5	−1.41	0.00353
201059_at	CTTN	1.50	0.00476
39402_at	IL1B	−2.04	0.00482
206167_s_at	ARHGAP6	1.41	0.00559
202729_s_at	LTBP1	1.49	0.00655
206655_s_at	GP1BB	1.76	0.00723
209774_x_at	CXCL2	−2.06	0.00777
1555938_x_at	VIM	−1.72	0.00783
223717_s_at	ACRBP	1.45	0.01097
207815_at	PF4V1	1.56	0.01284
226188_at	HSPC159	1.55	0.01452
206493_at	ITGA2B	1.47	0.01458
206110_at	HIST1H3H	1.63	0.01473
208791_at	CLU	1.55	0.01535
235739_at	n/a	1.45	0.01675
241036_at	n/a	1.47	0.01763
229943_at	TRIM13	−1.45	0.01846
203574_at	NFIL3	1.50	0.02137
230170_at	OSM	1.55	0.02277
201058_s_at	MYL9	1.52	0.02642
NuGO_eht0298527_at	CLEC1B	1.55	0.02726
NuGO_eht0299289_at	C6orf25	1.40	0.02753
205442_at	MFAP3L	1.55	0.02858
241824_at	n/a	1.46	0.03054
227180_at	ELOVL7	1.51	0.03600
204622_x_at	NR4A2	1.78	0.03866
203936_s_at	MMP9	1.72	0.03998
207826_s_at	ID3	−1.44	0.04005
230097_at	GART	−1.43	0.04148
224823_at	MYLK	1.51	0.04278
229778_at	C12orf39	1.41	0.04288
236610_at	n/a	1.47	0.04456
220496_at	CLEC1B	1.41	0.04753
235885_at	n/a	1.49	0.04801

ISSN: 1865-3499