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Table 1 Number of genes encoding ZNP network proteins and number of total genes modulated in inflamed and non-inflamed tissue from CD patients

From: Zinc proteome interaction network as a model to identify nutrient-affected pathways in human pathologies

Parallels

Modulated ZNP

Modulated genes

Hypergeometric distribution (ZNP MA vs. ZNP in genome)

p value

1. Inflamed CD versus non-inflamed CD

152

382

0.003

2. Non-inflamed CD versus control

179

511

0.56

3. CD versus control terminal ileum

591

1,667

0.49

4. Inflamed CD versus control

87

311

0.99

  1. The p values listed in the last column were estimated by hypergeometric distribution and express the likelihood that ZNP network genes might be overrepresented within the modulated expression profiles compared to their occurrence within the human genome