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Table 1 Relative mRNA expression and fold changes of IL-, IL-6 and TNF-α in PBMC (mean ± SEM)

From: TNF-α gene expression is increased following zinc supplementation in type 2 diabetes mellitus

 

Placebo (n = 10)

FSO (n = 10)

Zn (n = 11)

Zn + FSO (n = 9)

IL-

Week 0

0.96 ± 0.11

1.72 ± 0.39

1.04 ± 0.15

0.91 ± 0.14

Week 12

0.97 ± 0.02

1.33 ± 0.06

1.46 ± 0.01

0.98 ± 0.06

Fold change

1.08 ± 0.24

0.88 ± 0.43

1.51 ± 0.30

1.21 ± 0.35

IL-6

Week 0

0.10 ± 0.12

0.13 ± 0.25

0.05 ± 0.36

0.17 ± 0.13

Week 12

0.08 ± 0.02

0.14 ± 0.08

0.08 ± 0.02

0.26 ± 0.10

Fold change

0.97 ± 0.30

1.24 ± 0.29

1.46 ± 0.48

1.38 ± 023

TNF-α

Week 0

2.86 ± 0.15

3.85 ± 0.16

2.77 ± 0.26

2.89 ± 0.18

Week 12

3.01 ± 0.12

3.16 ± 0.27

3.64 ± 0.25

3.09 ± 0.23

Fold change

1.10 ± 0.12

0.88 ± 0.12

1.38 ± 0.16

1.14 ± 0.10

  1. FSO flaxseed oil, IL- interleukin-1β, IL-6, interleukin-6, TNF-α tumour necrosis factor-α, PBMC peripheral blood mononuclear cells
  2. Relative mRNA expression expressed as copies of mRNA per 106 18S rRNA
  3. Fold change data are calculated using the ΔΔC p method and expressed on a log scale