Skip to main content

Table 1 Relative mRNA expression and fold changes of IL-, IL-6 and TNF-α in PBMC (mean ± SEM)

From: TNF-α gene expression is increased following zinc supplementation in type 2 diabetes mellitus

  Placebo (n = 10) FSO (n = 10) Zn (n = 11) Zn + FSO (n = 9)
IL-
Week 0 0.96 ± 0.11 1.72 ± 0.39 1.04 ± 0.15 0.91 ± 0.14
Week 12 0.97 ± 0.02 1.33 ± 0.06 1.46 ± 0.01 0.98 ± 0.06
Fold change 1.08 ± 0.24 0.88 ± 0.43 1.51 ± 0.30 1.21 ± 0.35
IL-6
Week 0 0.10 ± 0.12 0.13 ± 0.25 0.05 ± 0.36 0.17 ± 0.13
Week 12 0.08 ± 0.02 0.14 ± 0.08 0.08 ± 0.02 0.26 ± 0.10
Fold change 0.97 ± 0.30 1.24 ± 0.29 1.46 ± 0.48 1.38 ± 023
TNF-α
Week 0 2.86 ± 0.15 3.85 ± 0.16 2.77 ± 0.26 2.89 ± 0.18
Week 12 3.01 ± 0.12 3.16 ± 0.27 3.64 ± 0.25 3.09 ± 0.23
Fold change 1.10 ± 0.12 0.88 ± 0.12 1.38 ± 0.16 1.14 ± 0.10
  1. FSO flaxseed oil, IL- interleukin-1β, IL-6, interleukin-6, TNF-α tumour necrosis factor-α, PBMC peripheral blood mononuclear cells
  2. Relative mRNA expression expressed as copies of mRNA per 106 18S rRNA
  3. Fold change data are calculated using the ΔΔC p method and expressed on a log scale