TNF-α gene expression is increased following zinc supplementation in type 2 diabetes mellitus

Genes & Nutrition

Table 3 Multiple regression models using expression of zinc transporters and metallothionein to predict IL-1β expression at baseline (model 1) and week 12 (model 2) for all participants

Factors	Model 1 (week 0)	n = 38	P value	Model 2 (week 12)	n = 37	P value
Factors	Regression coefficient	Standard error	P value	Regression coefficient	Standard error	P value
ZnT1	−0.02	0.04	0.58	0.02	0.07	0.75
ZnT5	−0.01	0.34	0.97	−0.64	0.39	0.12
ZnT6	−0.19	0.23	0.41	−0.09	0.30	0.78
ZnT7	0.06	0.07	0.38	0.30	0.09	0.002
ZnT8	−1.38	2.31	0.55	−4.81	4.55	0.30
Zip1	0.18	0.07	0.02	−0.01	0.09	0.89
Zip3	0.11	0.11	0.35	0.12	0.14	0.41
Zip7	−0.34	0.13	0.01	−0.17	0.26	0.53
Zip10	−0.01	0.09	0.91	−0.11	0.12	0.34
MT-1A	−0.11	0.10	0.28	−0.14	0.16	0.40
MT-2A	0.05	0.22	0.82	0.32	0.44	0.48
Overall	r ² = 0.495		0.04	r ² = 0.532		0.02

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