Table 2 Ten most significant pathways affected by polymeric formula treatment of TNF-stimulated colonic epithelium cells
Pathway | FD | Genes |
|---|---|---|
Transcription_NF-κB activation pathways | 1.5E−04 | NFKBIE, NFKB1, RELB, BIRC2, BIRC3, TNF |
Development_PEDF signalling | 8.5E−04 | NFKB1, BIRC2, BIRC3, VEGFA |
Development_VEGF signalling and activation | 2.5E−03 | HRAS, NFKBIE, NFKB1, VEGFA, PLCG1, FOS |
Apoptosis and survival_anti-apoptotic | 2.5E−03 | NFKBIE, NFKB1, BIRC2, BIRC3, TNF |
FGF signalling in pancreatic cancer | 2.5E−03 | HRAS, NFKB1, VEGFA, FGFR2, PLCG1 1, FOS |
Transcription_ligand-dependent activation of the ESR1/SP | 2.5E−03 | CDC25A, CAD, VEGFA, CARM1, FOS |
Gamma-secretase regulation of angiogenesis | 2.5E−03 | Csk, NOTCH1, VEGFA |
Transcription_N-CoR/SMRT complex-mediated epigenetic | 2.5E−03 | NFKB1, RXRB, BRG1, THRB, RXRB, FOS |
PDE4 regulation of cyto/chemokine expression in arthritis | 2.5E−03 | NFKB1, PRKACA, NFKBIE, CARD8, TNF |
Immune response_T cell receptor signalling pathway | 3.3E−03 | HRAS, BCL10, NFKBIE, NFKB1, PLCG1, FOS |