Skip to main content
Fig. 1 | Genes & Nutrition

Fig. 1

From: 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation

Fig. 1

Photomicrographs of H&E-stained liver sections of control, CP, and CP rats pretreated with 18β-GA. a Liver section of control rat showing normal histological structure, b–d liver sections of CP-induced rats showing hepatocellular focal degeneration and necrosis (n), hyperchromatic nuclei (blue arrows), hepatic cell karyolysis (asterisk), fatty degeneration (white arrow), cytoplasmic vacuolations (v), hydropic degeneration of hepatocytes, leukocytes infiltration, and hyperproliferation around the deformed bile ducts, dysplasia, karyomegaly, nuclear atypia (brown arrows), and some fibrotic changes, e liver section of rats pretreated with 25 mg 18-β GA showing normal hepatocytes and mild central vain and sinusoid congestion, and f liver section of rats pretreated with 50 mg 18-β GA showing normal hepatocytes with mild degeneration (×400)

Back to article page

Genes & Nutrition

ISSN: 1865-3499

Contact us