Pro12Pro (n = 17) | Ala12Ala (n = 14) | Baseline | Whole study | ||||
---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | P † | P ‡ | FDR§ | |
Age (years) | 56.7 | 7.2 | 62.1 | 7.3 | 0.048* | ||
Weight (kg) | 82.1 | 8.4 | 83.5 | 12.7 | 0.715 | 0.660 | 0.777 |
Body mass index (kg/m2) | 26.0 | 2.4 | 26.9 | 3.4 | 0.406 | 0.271 | 0.492 |
Fasting plasma glucose (mmol/l) | 5.8 | 0.4 | 5.7 | 0.5 | 0.857 | 0.479 | 0.713 |
Fasting plasma insulin (mU/l) | 49.2 | 24.6 | 49.0 | 20.1 | 0.967 | 0.758 | 0.803 |
Fasting plasma FFA (mmol/l) | 0.44 | 0.13 | 0.42 | 0.11 | 0.601 | 0.751 | 0.803 |
Total cholesterol (mmol/l) | 5.38 | 0.81 | 4.81 | 0.81 | 0.062 | 0.003* | 0.009* |
HDL cholesterol (mmol/l) | 1.24 | 0.25 | 1.52 | 0.45 | 0.039* | 0.077 | 0.365 |
LDL cholesterol (mmol/l) | 3.38 | 0.66 | 2.76 | 0.62 | 0.013* | 2 × 10−4 * | 9 × 10−4 * |
Total triglycerides (mmol/l) | 1.38 | 0.49 | 0.85 | 0.28 | 0.001* | 4 × 10−4 * | 0.001* |
Apolipoprotein A1 (g/l) | 1.39 | 0.17 | 1.43 | 0.24 | 0.596 | 0.661 | 0.777 |
Apolipoprotein B (g/l) | 1.05 | 0.18 | 0.83 | 0.14 | 0.001* | 2 × 10−5 * | 3 × 10−4 * |