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Table 2 GO analysis (mRNA arrays)

From: Characterization of the hypothalamic transcriptome in response to food deprivation reveals global changes in long noncoding RNA, and cell cycle response genes

GO term

Gene count (significant)

Gene count (reference)

P value

Biological process

GO:0006810: transport

56

1620

8.73E−07

GO:0007049: cell cycle

26

533

3.41E−05

GO:0016310: phosphorylation

29

689

8.99E−05

GO:0048812: neuron projection morphogenesis

7

36

0.000192

GO:0006974: response to DNA damage stimulus

17

308

0.000447

Cellular component

GO:0016020: membrane

178

5723

4.76E−24

GO:0005886: plasma membrane

103

2782

1.23E−17

GO:0005634: nucleus

144

4867

7.00E−17

GO:0005737: cytoplasm

141

5026

1.33E−14

GO:0016021: integral to membrane

143

5398

6.95E−13

Molecular function

GO:0005515: protein binding

100

2999

3.92E−16

GO:0046872: metal ion binding

91

2802

5.08E−14

GO:0000166: nucleotide binding

64

1999

8.20E−10

GO:0005524: ATP binding

47

1421

6.59E−08

GO:0003677: DNA binding

51

1635

1.10E−07

KEGG pathways

KEGG:04670: leukocyte transendothelial migration

9

117

4.27E−05

KEGG:04724: glutamatergic synapse

9

123

6.32E−05

KEGG:04010: MAPK signaling pathway

10

263

0.004306

KEGG:04144: endocytosis

9

213

0.003344

KEGG:04062: chemokine signaling pathway

12

177

8.61E−06

  1. All significantly differentially expressed mRNAs (529 total) were used in this analysis. The top five GO terms for each category are shown. The number of genes significant for that category (gene count, significant), the number of total genes in the reference category (gene count, reference) and P value for the GO term are shown