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Fig. 6 | Genes & Nutrition

Fig. 6

From: Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells

Fig. 6

Model that integrates the potential pathways by which MET and soy bioactives influence the frequency of cancer stem-like cell population. The pathways demonstrate the involvement of the tumor suppressor PTEN and the lipid biosynthesis-associated enzyme FASN under obesogenic/diabetic conditions. Designations (→, ⊥) indicate promotion and inhibition, respectively, of a specific pathway. The identities of other possible pathways mediated by soy bioactives are unknown (indicated by question mark)

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Genes & Nutrition

ISSN: 1865-3499

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