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Table 3 Serum glucose level and lipid profile at post treatment days 15 and 30

From: Comparative anti-inflammatory and lipid-normalizing effects of metformin and omega-3 fatty acids through modulation of transcription factors in diabetic rats

  Control (n = 6) STZ (n = 6) Metformin (n = 6) Flax oil (n = 6) Fish oil (n = 6)
Glucose level (mg/dl)
 At day 15 53.72 ± 3.58 294.11 ± 14.85** 340.98 ± 30.14 280.12 ± 12.62 315.36 ± 10.66
 At day 30 54.11 ± 4.89 309.65 ± 33.54** 300.64 ± 6.75 315.18 ± 16.20 269.23 ± 16.96
Lipid profile
 Post treatment day 15
  Cholesterol (mg/dl) 43.37 ± 3.76 98.24 ± 12.83** 58.79 ± 4.47# 87.31 ± 9.03 69.44 ± 3.16
  Triglyceride (mg/dl) 72.74 ± 6.15 171.96 ± 39.49 145.58 ± 20.68 114.01 ± 15.45 133.95 ± 23.67
  HDL (mg/dl) 10.03 ± 0.83 22.10 ± 2.11** 8.09 ± 1.55## 22.93 ± 1.95 13.80 ± 1.17#
  LDL (mg/dl) 17.31 ± 1.44 38.12 ± 3.65** 13.96 ± 2.68## 39.56 ± 3.37 23.82 ± 2.20#
  VLDL (mg/dl) 14.54 ± 1.23 34.39 ± 7.89 29.19 ± 4.13 22.80 ± 3.09 26.79 ± 4.73
 Post treatment day 30
  Cholesterol (mg/dl) 44.44 ± 2.04 68.22 ± 10.04* 34.35 ± 4.71## 49.25 ± 2.82 34.62 ± 4.75##
  Triglyceride (mg/dl) 66.29 ± 5.96 201.33 ± 31.23** 43.14 ± 8.12## 44.81 ± 11.19## 42.03 ± 9.13##
  HDL (mg/dl) 10.71 ± 0.70 9.95 ± 1.10 7.97 ± 1.02 13.05 ± 1.06 8.73 ± 0.71
  LDL (mg/dl) 18.48 ± 1.21 17.16 ± 1.90 13.75 ± 1.77 22.52 ± 1.83 15.05 ± 1.23
  VLDL (mg/dl) 13.25 ± 1.19 40.26 ± 6.24** 8.62 ± 1.62## 8.96 ± 2.23## 8.40 ± 1.82##
  1. Data are presented as mean ± SE
  2. HDL high-density lipoprotein cholesterol, LDL low-density lipoprotein cholesterol, VLDL very low-density lipoprotein cholesterol
  3. *p < 0.05, **p < 0.01 for comparison between the control and STZ group and # p < 0.05, ## p < 0.01 for comparison between the STZ group and treatment groups