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Table 3 Serum glucose level and lipid profile at post treatment days 15 and 30

From: Comparative anti-inflammatory and lipid-normalizing effects of metformin and omega-3 fatty acids through modulation of transcription factors in diabetic rats

 

Control (n = 6)

STZ (n = 6)

Metformin (n = 6)

Flax oil (n = 6)

Fish oil (n = 6)

Glucose level (mg/dl)

 At day 15

53.72 ± 3.58

294.11 ± 14.85**

340.98 ± 30.14

280.12 ± 12.62

315.36 ± 10.66

 At day 30

54.11 ± 4.89

309.65 ± 33.54**

300.64 ± 6.75

315.18 ± 16.20

269.23 ± 16.96

Lipid profile

 Post treatment day 15

  Cholesterol (mg/dl)

43.37 ± 3.76

98.24 ± 12.83**

58.79 ± 4.47#

87.31 ± 9.03

69.44 ± 3.16

  Triglyceride (mg/dl)

72.74 ± 6.15

171.96 ± 39.49

145.58 ± 20.68

114.01 ± 15.45

133.95 ± 23.67

  HDL (mg/dl)

10.03 ± 0.83

22.10 ± 2.11**

8.09 ± 1.55##

22.93 ± 1.95

13.80 ± 1.17#

  LDL (mg/dl)

17.31 ± 1.44

38.12 ± 3.65**

13.96 ± 2.68##

39.56 ± 3.37

23.82 ± 2.20#

  VLDL (mg/dl)

14.54 ± 1.23

34.39 ± 7.89

29.19 ± 4.13

22.80 ± 3.09

26.79 ± 4.73

 Post treatment day 30

  Cholesterol (mg/dl)

44.44 ± 2.04

68.22 ± 10.04*

34.35 ± 4.71##

49.25 ± 2.82

34.62 ± 4.75##

  Triglyceride (mg/dl)

66.29 ± 5.96

201.33 ± 31.23**

43.14 ± 8.12##

44.81 ± 11.19##

42.03 ± 9.13##

  HDL (mg/dl)

10.71 ± 0.70

9.95 ± 1.10

7.97 ± 1.02

13.05 ± 1.06

8.73 ± 0.71

  LDL (mg/dl)

18.48 ± 1.21

17.16 ± 1.90

13.75 ± 1.77

22.52 ± 1.83

15.05 ± 1.23

  VLDL (mg/dl)

13.25 ± 1.19

40.26 ± 6.24**

8.62 ± 1.62##

8.96 ± 2.23##

8.40 ± 1.82##

  1. Data are presented as mean ± SE
  2. HDL high-density lipoprotein cholesterol, LDL low-density lipoprotein cholesterol, VLDL very low-density lipoprotein cholesterol
  3. *p < 0.05, **p < 0.01 for comparison between the control and STZ group and # p < 0.05, ## p < 0.01 for comparison between the STZ group and treatment groups