Skip to main content
Fig. 2 | Genes & Nutrition

Fig. 2

From: Curcumin and tetrahydrocurcumin both prevent osteoarthritis symptoms and decrease the expressions of pro-inflammatory cytokines in estrogen-deficient rats

Fig. 2

Tail skin temperature at the third and seventh weeks of the experimental periods. Ovariectomized (OVX) rats were provided with a 45 % fat diet containing (1) 0.4 % curcumin, (2) 0.4 % tetrahydrocurcumin (THC), (3) 30 μg/kg body weight 17β-estradiol + 0.4 % dextrin (positive control), (4) 0.4 % dextrin (control), or (5) 0.4 % dextrin (normal control for osteoarthritis). At the beginning of the fifth week, an articular injection of monoiodoacetate into the right knee was performed on all OVX groups except the normal-control group and the assigned diets were provided for an additional 3 weeks. Rats in the normal-control group had articular injections of saline in the right knee. Tail skin temperature was measured at the fourth and seventh weeks. Each bar represents mean ± SD (n = 10). (a, b) The bars with different letters were significantly different among groups by the Tukey test at P < 0.05

Back to article page