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Fig. 3 | Genes & Nutrition

Fig. 3

From: Circulating microRNAs are deregulated in overweight/obese children: preliminary results of the I.Family study

Fig. 3

C/EBPα, a key target. The C/EBPα intronless gene encodes a transcription factor containing a basic leucine zipper domain. The protein acts in homodimers or heterodimers that recognize the CCAAT motifs in the promoters of target genes. Complexes modulate the expression of genes involved in cell cycle regulation as well as adipocyte functions: during adipogenesis highly induced genes are synergistically controlled by both PPARγ and C/EBPα

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Genes & Nutrition

ISSN: 1865-3499

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