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Table 3 Differential miRNA profile confirmed by RT-qPCR

From: Circulating microRNAs are deregulated in overweight/obese children: preliminary results of the I.Family study

miRNA

OW/Ob

NW

Fold regulation

p

 

miR-31-5p

3.60 (3.42–3.97)

1.86 (0.47–2.40)

1.92

0.0003

↑

miR-2355-5p

3.65 (2.52–5.35)

1.23 (0.21–1.78)

2.93

0.0166

↑

miR-206

1.28 (0.63–1.83)

2.45 (1.29–4.92)

0.52

0.0461

↓

  1. Differential miRNAs were confirmed by RT-qPCR. Reported values are mean (minimum-maximum). Fold regulation was expressed as fold change with respect to non-obese controls. Reference included the endogenous spike-in C.el-miR-39-3p
  2. up arrow = upregulated; down arrow = downregulated