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Table 4 MiRPath analysis

From: Circulating microRNAs are deregulated in overweight/obese children: preliminary results of the I.Family study

KEGG pathway

p value

Gap junction

1.13E-13

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

2.90E-05

Notch signaling pathway

0.0003

Regulation of actin cytoskeleton

0.0005

Dorso-ventral axis formation

0.0008

Bacterial invasion of epithelial cells

0.0009

Axon guidance

0.0026

Shigellosis

0.0200

Endocrine and other factor-regulated calcium reabsorption

0.0397

Glycosaminoglycan biosynthesis—heparan sulfate/heparin

0.0483

Pathways in cancer

0.0490

Thyroid cancer

0.0500

  1. Target genes were classified according to KEGG functional annotations to identify top pathways that were actively regulated by miRNAs. Merged p value is extracted by combining calculated significance levels using Fisher’s meta-analysis method