The PBMC transcriptome profile after intake of oxidized versus high-quality fish oil: an explorative study in healthy subjects

Table 3 GSEA analyses. Gene sets associated with oxidative stress and cardiovascular diseases created using a gene set browser (Molecular Signatures Database v5.0)

GSEA gene set collection^a	# gene sets in collection^b	Regulated gene sets oxFO vs FO (FDR q value < 0.25)
oxidative AND stress	46	0
oxidative AND damage	5	0
hypoxi*	65	0
cardiovascular*	13	0
immune AND response	147	0
inflammation	29	0

# number of gene sets, FDR false discovery rate
* indicates truncated search words
^aCollections of gene sets were obtained using a gene set browser from the Broad Institute website http://software.broadinstitute.org/gsea/msigdb/search.jsp by the listed keywords
^bNumber of gene sets passing the gene set size filter (min 10 genes, max 500 genes)

ISSN: 1865-3499