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Table 1 The list of the differently regulated EFA-CLA vs. EFA specific transcripts in MCF-7 cell line

From: Fatty acid extract from CLA-enriched egg yolks can mediate transcriptome reprogramming of MCF-7 cancer cells to prevent their growth and proliferation

Gene Symbol

Adjusted p values

FC value

Gene name

NOTCH1

0.0146

−2.63

Notch homolog 1, translocation-associated

AGPS

0.0424

−2.19

Alkylglycerone phosphate synthase

GNA12

0.0009

−1.56

Guanine nucleotide binding protein (G protein) alpha 12

HIF1A

0.0184

−1.56

Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

STAT3

0.0088

−1.32

Signal transducer and activator of transcription 3 (acute-phase response factor)

UCP2

0.0083

−1.29

Uncoupling protein 2 (mitochondrial, proton carrier)

HIGD2A

0.0089

−1.27

HIG1 hypoxia inducible domain family, member 2A

WASH1

0.0038

−1.27

WAS protein family homolog 1

BIN3

0.0477

−1.16

Bridging integrator 3

PRKAR1A

0.0462

−1.14

Protein kinase, cAMP-dependent, regulatory, type I, alpha

NDUFB11

0.0105

−1.13

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3 kDa

ANXA5

0.0311

−1.05

Annexin A5

SMS

0.0399

1.08

Spermine synthase

PPP2R5E

0.0009

1.13

Protein phosphatase 2, regulatory subunit B', epsilon isoform

NAP1L1

0.0335

1.14

Nucleosome assembly protein 1-like 1

PTEN

0.0382

1.15

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

LOC646214

0.0213

1.16

p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene

LMCD1

0.0067

1.21

LIM and cysteine-rich domains 1

CAMSAP2

0.0174

1.23

Calmodulin regulated spectrin-associated protein family, member 2

TSC2

0.0177

1.26

Tuberous sclerosis 2

FLJ45139

0.0406

1.33

FLJ45139 protein

CHSY3

0.0399

1.72

Chondroitin sulfate synthase 3

OVOS

0.0403

1.72

Ovostatin

SCD

0.19

−1.18NS

Stearoyl-CoA desaturase (delta-9-desaturase)

  1. Statistical significance of treatment: p < 0.05; NS p > 0.05; bolded genes are to be associated with cancer