Fig. 2

Transcriptome profiling analysis of the kidneys in dehydrated and control mice using genome-scale Illumina microarray. a The weight of the kidney increased with age, but dehydration caused decreased weight in the kidneys of infant mice (RES 1W) by 22 % and in juvenile mice (RES 4W) by 8 %. b A 3D principal component analysis (PCA) plot of the renal transcriptome data represents significantly distinguishable profiles for each group: CON 1W (light blue), RES 1W (orange), CON 4W (blue), and RES 4W (red). Each dot indicates an individual kidney sample. c The Venn diagram shows the number of probes that were detected with different signal intensity in each dataset. Data are expressed as mean ± SEM. Student’s t test; **p < 0.01, ***p < 0.001 versus control group