Table 4 List of genes significantly regulated by PFJ

  Sds

Serine dehydratase

51.92

4.95

  Plekhb1

Pleckstrin homology domain containing, family B (evectins) member 1

45.01

3.66

  Npc1l1

Niemann-Pick C1-like 1

30.36

7.41

  EG240549

Predicted gene, EG240549

25.98

3.13

  F7

Coagulation factor VII

23.44

3.08

  Ecm1

Extracellular matrix protein 1

23.18

2.32

  Enpp2

Ectonucleotide pyrophosphatase/phosphodiesterase 2

21.76

2.50

  Ugt2b36

UDP glucuronosyltransferase 2 family, polypeptide B36

21.09

2.98

  Hdac3

Histone deacetylase 3

20.37

2.93

  Cspg5

Chondroitin sulphate proteoglycan 5

20.27

2.05

  Cyp2c67

Cytochrome P450, family 2, subfamily c, polypeptide 67

20.06

14.08

  Specc1l

SPECC1-like

20.05

1.83

  Cps1

Carbamoyl-phosphate synthetase 1, nuclear gene encoding mitochondrial protein XM_993466

19.42

2.78

  Hbb-b1

Haemoglobin, beta adult major chain

19.19

2.14

  Tnrc6a

Trinucleotide repeat containing 6a

19.03

1.58

  Rps7

Ribosomal protein S7

18.21

1.76

  Apoc1

Apolipoprotein C-I

17.47

13.49

  Cyp2e1

Cytochrome P450, family 2, subfamily e, polypeptide 1

16.93

2.33

  Ifrd1

Interferon-related developmental regulator 1

16.84

1.94

  Mup2

Major urinary protein 2, transcript variant 1

16.51

197.62

  Rpn2

Ribophorin II

16.41

2.07

  Asl

Argininosuccinate lyase

16.33

1.85

  Ptprt

Protein tyrosine phosphatase, receptor type, T

16.06

2.78

  Bcdo2

Beta-carotene 9', 10'-dioxygenase 2

16.00

2.43

  Zfhx2

Zinc finger homeobox 2

15.95

1.77

  Mthfd1

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

15.95

1.54

  Rnf215

Ring finger protein 215

15.91

1.63

  Gne

Glucosamine

15.82

2.54

  Cyp4f14

Cytochrome P450, family 4, subfamily f, polypeptide 14

15.60

2.55

  Zxda

Zinc finger, X-linked, duplicated A

15.35

1.51

  Nat1

N-acetyltransferase 1 (arylamine N-acetyltransferase)

15.26

2.05

  Cat

Catalase

15.23

2.84

  Tyms-ps

Thymidylate synthase, pseudogene

15.16

1.69

  F5

Coagulation factor V

15.12

2.38

  Fbxo7

F-box only protein 7

14.96

1.71

  Apoa2

Apolipoprotein A-II

14.91

2.67

  Hagh

Hydroxyacyl glutathione hydrolase

14.87

1.64

  Alas1

Aminolevulinic acid synthase 1

14.80

10.33

  Inmt

Indolethylamine N-methyltransferase

14.79

2.62

  620807.00

Predicted gene, 620807

14.78

106.29

  Hsd17b10

Hydroxysteroid (17-beta) dehydrogenase 10, nuclear gene encoding mitochondrial protein

14.75

2.30

  Nr1i3

Nuclear receptor subfamily 1, group I, member 3

14.63

2.02

  Nit2

Nitrilase family, member 2

14.58

1.99

  Tbc1d15

TBC1 domain family, member 15

14.57

1.71

  Apoc3

Apolipoprotein C-III

14.56

2.77

  ORF61

Open reading frame 61

14.51

1.54

  Ephx1

Epoxide hydrolase 1, microsomal

14.36

2.98

  Serpina1d

Serine (or cysteine) peptidase inhibitor, clade A, member 1d

14.26

13.47

  Stab1

Stabilin 1

14.19

2.00

  Ifitm2

Interferon induced transmembrane protein 2

14.05

1.55

  Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2, nuclear gene encoding mitochondrial protein

14.03

5.41

  Serpina1b

Serine (or cysteine) preptidase inhibitor, clade A, member 1b

14.03

13.48

  Tmem132e

Transmembrane protein 132E

13.98

1.99

  Syvn1

Synovial apoptosis inhibitor 1, synoviolin

13.97

1.78

  Cyp1a2

Cytochrome P450, family 1, subfamily a, polypeptide 2

13.92

2.38

  Reln

Reelin

13.90

2.44

  Fzd7

Frizzled homologue 7 (Drosophila)

13.87

1.96

  F13b

Coagulation factor XIII, beta subunit

13.83

2.30

  Rpl36al

Ribosomal protein l36a-like

13.73

1.79

  Klkb1

Kallikrein B, plasma 1

13.72

2.29

  Sdf2

Stromal cell derived factor 2

13.53

1.44

  3110049J23Rik

RIKEN cDNA 3110049 J23 gene

13.44

1.70

  2810004N20Rik

RIKEN cDNA 2810004 N20 gene

13.40

1.74

  Rxrg

Retinoid X receptor gamma

13.36

2.29

  Ces3

Carboxylesterase 3

13.20

4.77

  Sec16b

SEC16 homologue B (Saccharomyces cerevisiae)

13.20

2.31

  Gsto2

Glutathione S-transferase omega 2

13.17

2.33

  5830404H04Rik

RIKEN cDNA 5830404H04 gene

13.14

1.90

  Creld1

Cysteine-rich with EGF-like domains 1

13.13

1.46

  Mat1a

Methionine adenosyltransferase I, alpha

13.04

14.39

  Apoa1

Apolipoprotein A-I

13.02

25.82

  St3gal6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

−13.09

−21.14

  Btbd3

BTB (POZ) domain containing 3

−13.12

−2.51

  Wbp2

WW domain binding protein 2

−13.12

−1.47

  LOC100045542

Predicted: similar to FERMRhoGEF (Arhgef) and pleckstrin domain protein 1

−13.14

−3.04

  Shmt2

Serine hydroxymethyltransferase 2 (mitochondrial), nuclear gene encoding mitochondrial protein

−13.19

−1.69

  Clptm1l

CLPTM1-like

−13.24

−1.48

  Cox10

COX10 homologue, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast), nuclear gene encoding mitochondrial protein

−13.26

−1.54

  Gpr107

G protein-coupled receptor 107

−13.27

−1.82

  Dnajc10

Dnaj (Hsp40) homologue, subfamily C, member 10

−13.29

−1.55

  Plod2

Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

−13.29

−2.74

  Magee1

Melanoma antigen, family E, 1

−13.31

−4.06

  Ppp1r16a

Protein phosphatase 1, regulatory (inhibitor) subunit 16A

−13.35

−2.19

  Prkcbp1

Protein kinase C binding protein 1

−13.36

−2.04

  Map3k11

Mitogen-activated protein kinase kinase kinase 11

−13.37

−1.48

  Marcks

Myristoylated alanine rich protein kinase C substrate

−13.38

−1.47

  Tex9

Testis expressed gene 9

−13.39

−2.46

  Cog1

Component of oligomeric golgi complex 1

−13.40

−1.51

  Slc39a13

Solute carrier family 39 (metal ion transporter), member 13

−13.40

−2.66

  Fam110b

Family with sequence similarity 110, member B

−13.43

−3.23

  Cox6b1

Cytochrome c oxidase, subunit VIb polypeptide 1

−13.44

−1.45

  Stxbp2

Syntaxin binding protein 2

−13.45

−1.68

  Ino80b

INO80 complex subunit B

−13.45

−2.52

  Nap1l4

Nucleosome assembly protein 1-like 4

−13.45

−1.55

  Flii

Flightless I homologue (Drosophila)

−13.47

−1.63

  Ahdc1

AT hook, DNA binding motif, containing 1

−13.55

−1.63

  Nol5a

Nucleolar protein 5A

−13.69

−1.52

  2400001E08Rik

RIKEN cDNA 2400001E08 gene

−13.75

−1.77

  Prmt5

Protein arginine N-methyltransferase 5

−13.77

−1.79

  Tinagl

Tubulointerstitial nephritis antigen-like

−13.78

−3.14

  Parl

Presenilin associated, rhomboid-like

−13.84

−1.51

  Zmat5

Zinc finger, matrin type 5

−13.85

−1.86

  Calm3

Calmodulin 3

−13.86

−2.15

  Ak3l1

Adenylate kinase 3-like 1, nuclear gene encoding mitochondrial protein

−13.86

−1.49

  2700087H15Rik

RIKEN cDNA 2700087H15 gene

−13.93

−1.54

  Grit

RHOGTPase-activating protein

−13.95

−2.23

  X99384

cDNA sequence X99384

−13.96

−1.77

  Ddx27

DEAD (Asp-Glu-Ala-Asp) box polypeptide 27

−13.97

−2.09

  Zfp313

Zinc finger protein 313

−13.98

−1.53

  D15Wsu169e

DNA segment, Chr 15, Wayne State University 169, expressed

−14.02

−4.17

  Zer1

Zer-1 homologue (Caenorhabditis elegans)

−14.03

−2.01

  Snapc2

Small nuclear RNA activating complex, polypeptide 2

−14.05

−2.04

  Dock1

Dedicator of cytokinesis 1

−14.19

−1.91

  Pak4

P21 (CDKN1A)-activated kinase 4

−14.21

−1.51

  Arl2

ADP-ribosylation factor-like 2

−14.22

−6.24

  Pcolce

Procollagen C-endopeptidase enhancer protein

−14.24

−2.15

  1110018G07Rik

RIKEN cDNA 1110018G07 gene

−14.28

−1.61

  2610528J11Rik

RIKEN cDNA 2610528J11 gene

−14.29

−2.35

  Akp2

Alkaline phosphatase 2, liver

−14.31

−2.72

  Mapre1

Microtubule-associated protein, RP/EB family, member 1

−14.35

−1.56

  Tmem138

Transmembrane protein 138

−14.36

−2.51

  Pacs2

Phosphofurin acidic cluster sorting protein 2

−14.41

−1.70

  LOC100047173

PREDICTED: similar to synaptotagmin-like 1

−14.41

−3.34

  Ano10

Anoctamin 10

−14.47

−5.94

  Vasn

Vasorin

−14.48

−1.65

  Cml4

Camello-like 4

−14.50

−3.02

  Clcn3

Chloride channel 3, transcript variant a

−14.50

−1.73

  Pik3r3

Phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55)

−14.54

−4.60

  Timp1

TIMP metallopeptidase inhibitor 1

−14.61

−1.60

  Fbxl15

F-box and leucine-rich repeat protein 15

−14.65

−1.59

  Npc2

Niemann-Pick disease, type C2

−14.68

−1.60

  Mrps33

Mitochondrial ribosomal protein S33, nuclear gene encoding mitochondrial protein, transcript variant 2

−14.73

−1.65

  Pgam5

Phosphoglycerate mutase family member 5

−14.73

−1.84

  2310005N01Rik

RIKEN cDNA 2310005N01 gene

−14.79

−2.67

  Ctdspl

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

−14.83

−2.49

  LOC100046039

PREDICTED: similar to histone deacetylase HD1

−14.85

−2.29

  Gnptab

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

−14.93

−1.90

  Tbc1d14

TBC1 domain family, member 14

−15.03

−2.88

  Cyr61

Cysteine-rich protein 61

−15.07

−4.37

  Gdpd1

Glycerophosphodiester phosphodiesterase domain containing 1

−15.11

−1.58

  2310022B05Rik

RIKEN cDNA 2310022B05 gene

−15.16

−1.53

  Asna1

Arsa arsenite transporter, ATP-binding, homologue 1 (bacterial)

−15.16

−1.66

  Tcf4

Transcription factor 4, transcript variant 1

−15.17

−2.10

  Vps26b

Vacuolar protein sorting 26 homologue B (yeast)

−15.43

−1.57

  Nf2

Neurofibromatosis 2

−15.54

−2.64

  LOC192758

Similar to hypothetical protein MGC39650

−15.63

−3.10

  Drg2

Developmentally regulated GTP binding protein 2

−15.66

−1.74

  Iqgap1

IQ motif containing GTPase activating protein 1

−15.89

−1.73

  Nrp1

Neuropilin 1

−16.05

−2.33

  Tbc1d13

TBC1 domain family, member 13

−16.13

−3.24

  2310003P10Rik

RIKEN cDNA 2310003P10 gene

−16.15

−3.82

  Trim28

Tripartite motif protein 28

−16.18

−1.79

  Tlr2

Toll-like receptor 2

−16.41

−2.26

  0910001L09Rik

RIKEN cDNA 0910001L09 gene

−16.42

−2.15

  B930041F14Rik

RIKEN cDNA B930041F14 gene

−16.74

−2.44

  Nup93

Nucleoporin 93 kDa

−16.93

−2.22

  Lphn1

Latrophilin 1

−17.11

−2.08

  Odz4

Odd Oz/ten-m homologue 4 (Drosophila)

−17.13

−4.10

  Gnai2

Guanine nucleotide binding protein, alpha inhibiting 2

−17.14

−2.08

  Cyp4f13

Cytochrome P450, family 4, subfamily f, polypeptide 13

−17.16

−4.76

  Aacs

Acetoacetyl-coa synthetase

−17.26

−1.62

  Smarca4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

−17.42

−1.89

  Gatad2b

GATA zinc finger domain containing 2B

−17.46

−2.31

  Actr1b

ARP1 actin-related protein 1 homologue B, centractin beta (yeast)

−17.87

−1.74

  Neo1

Neogenin 1

−17.93

−2.00

  Meis2

Meis homeobox 2, transcript variant 2

−18.31

−1.91

  Serpinh1

Serine (or cysteine) peptidase inhibitor, clade H, member 1

−18.44

−9.72

  Cc2d2a

Coiled-coil and C2 domain containing 2A

−18.44

−2.28

  Vdac1

Voltage-dependent anion channel 1

−18.88

−1.65

  Picalm

Phosphatidylinositol binding clathrin assembly protein

−19.13

−1.73

  Ankrd24

Ankyrin repeat domain 24

−19.20

−6.41

  Pi4ka

Phosphatidylinositol 4-kinase, catalytic, alpha polypeptide

−19.52

−2.19

  Map3k2

Mitogen-activated protein kinase kinase kinase 2

−19.53

−3.51

  1700029G01Rik

RIKEN cDNA 1700029G01 gene

−19.78

−2.21

  Atn1

Atrophin 1

−21.42

−1.86

  Itprip

Inositol 1,4,5-triphosphate receptor interacting protein

−22.26

−6.38

  Gadd45g

Growth arrest and DNA-damage-inducible 45 gamma

−23.65

−2.44

  Ly6e

Lymphocyte antigen 6 complex, locus E

−23.91

−2.53

  Ctcfl

CCCTC-binding factor (zinc finger protein)-like

−27.64

−2.21