WikiPathway name | No. changed | % changed | Z score | Permuted p |
---|---|---|---|---|
Up-regulated WikiPathways | ||||
 Tryptophan metabolism:WP79 | 6 | 15.3846 | 9.4735 | 0.0000 |
 Aflatoxin B1 metabolism:WP1262 | 2 | 40.0000 | 9.1192 | 0.0005 |
 Methylation:WP1247 | 2 | 28.5714 | 7.6363 | 0.0000 |
 Fatty acid omega oxidation:WP33 | 2 | 28.5714 | 7.6363 | 0.0015 |
 Statin pathway (PharmGKB):WP1 | 3 | 16.6667 | 6.9838 | 0.0000 |
 Blood clotting cascade:WP460 | 3 | 15.7895 | 6.7763 | 0.0000 |
 Nuclear receptors in lipid metabolism and toxicity:WP431 | 3 | 10.0000 | 5.2068 | 0.0005 |
 Complement and coagulation cascades:WP449 | 4 | 6.8966 | 4.7841 | 0.0000 |
 Urea cycle and metabolism of amino groups:WP426 | 2 | 11.1111 | 4.5187 | 0.0020 |
 Retinol metabolism:WP1259 | 3 | 7.6923 | 4.4328 | 0.0005 |
 Metapathway biotransformation:WP1251 | 5 | 4.4248 | 3.9468 | 0.0000 |
 One-carbon metabolism:WP435 | 2 | 8.3333 | 3.7980 | 0.0040 |
 Nuclear receptors:WP509 | 2 | 5.5556 | 2.9123 | 0.0075 |
 Cytochrome P450:WP1274 | 2 | 5.2632 | 2.8039 | 0.0105 |
Down-Regulated WikiPathways | ||||
 Regulation of actin cytoskeleton:WP523 | 4 | 3.0534 | 3.6287 | 0.0080 |
 Insulin signalling:WP65 | 4 | 2.8169 | 3.4170 | 0.0110 |
 Endochondral ossification:WP1270 | 2 | 3.3898 | 2.7401 | 0.0460 |
 TNF-alpha NF-κβ signalling pathway:WP246 | 3 | 2.2222 | 2.4278 | 0.0430 |