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Table 3 Genes expressed differentially in response to high-fat diet at multiple time points in the colon tissue of C57BL/6N mice

From: Time-course microarray analysis for identifying candidate genes involved in obesity-associated pathological changes in the mouse colon

Symbol

Accession

Definition

Log2 fold change

Week 2

Week 4

Week 8

Week 12

AI747448

NM_001033199.2

Expressed sequence AI747448 (AI747448), mRNA.

1.14

−2.62

−1.88

 

Amy2

NM_009669.1

Amylase 2, pancreatic (Amy2), mRNA.

3.92

1.91

 

−4.93

Apoa4

NM_007468.2

Apolipoprotein A-IV (Apoa4), mRNA.

1.06

 

−1.20

−1.13

Cel

NM_009885.1

Carboxyl ester lipase (Cel), mRNA.

3.99

1.26

 

−3.88

Cfd

NM_013459.1

Complement factor D (adipsin) (Cfd), mRNA.

 

−1.93

−1.17

−1.19

Cpa2

NM_001024698.2

Carboxypeptidase A2, pancreatic (Cpa2), mRNA.

2.95

1.01

 

−1.91

Cpb1

NM_029706.1

Carboxypeptidase B1 (tissue) (Cpb1), mRNA.

4.35

1.31

 

−4.14

Ctrb1

NM_025583.1

Chymotrypsinogen B1 (Ctrb1), mRNA.

4.08

1.64

 

−2.84

Ctrl

NM_023182.2

Chymotrypsin-like (Ctrl), mRNA.

4.04

1.01

 

−3.52

Ela2a

NM_007919.2

Elastase 2A (Ela2a), mRNA.

5.52

1.08

 

−6.00

Ela3b

NM_026419.1

 

4.62

1.22

 

−4.12

LOC100040233

XM_001474605.1

Predicted: similar to trypsinogen 15 (LOC100040233), mRNA.

3.23

1.27

 

−2.06

Pla2g1b

NM_011107.1

Phospholipase A2, group IB, pancreas (Pla2g1b), mRNA.

3.79

1.34

 

−2.86

Rnase1

NM_011271.2

Ribonuclease, RNase A family, 1 (pancreatic) (Rnase1), mRNA.

4.27

1.29

 

−3.58

Try10

NM_001038996.1

Trypsin 10 (Try10), mRNA.

3.73

1.55

 

−2.84

Try4

NM_011646.5

Trypsin 4 (Try4), mRNA.

4.72

1.34

 

−3.67

  1. Log2 fold change of ≥1 or≤−1 corresponds to a fold change of ≥2 or ≤−2, respectively, based on a comparison between high-fat diet- and normal diet-fed mice at each time point (P < 0.05)