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Table 4 Genes in cluster 4

From: Time-course microarray analysis for identifying candidate genes involved in obesity-associated pathological changes in the mouse colon

Symbol

Accession

Definition

Log2 fold change

Week 2

Week 4

Week 8

Week 12

1810033M07Rik

NM_026983.1

RIKEN cDNA 1810033M07 gene (1810033M07Rik), mRNA.

1.30

0.67

0.22

−0.90

1810049H19Rik

NM_001003405.1

RIKEN cDNA 1810049H19 gene (1810049H19Rik), mRNA.

4.62

1.44

0.41

−3.66

2900060B14Rik

 

1.38

0.07

0.11

−0.36

Amy2

NM_009669.1

Amylase 2, pancreatic (Amy2), mRNA.

3.92

1.91

0.22

−4.93

Amy2-2

NM_001042711.2

Amylase 2-2, pancreatic (Amy2-2), mRNA.

4.02

0.44

0.82

−5.93

Apoa4

NM_007468.2

Apolipoprotein A-IV (Apoa4), mRNA.

1.06

0.57

−1.20

−1.13

Cel

NM_009885.1

Carboxyl ester lipase (Cel), mRNA.

3.99

1.26

0.04

−3.88

Clps

NM_025469.2

Colipase, pancreatic (Clps), mRNA.

2.28

0.49

−0.11

−0.70

Cpa1

XM_284174.1

 

4.89

0.78

0.15

−4.54

Cpa2

NM_001024698.2

Carboxypeptidase A2, pancreatic (Cpa2), mRNA.

2.95

1.01

0.18

−1.91

Cpb1

NM_029706.1

Carboxypeptidase B1 (tissue) (Cpb1), mRNA.

4.35

1.31

0.02

−4.14

Ctrb1

NM_025583.1

Chymotrypsinogen B1 (Ctrb1), mRNA.

4.08

1.64

0.04

−2.84

Ctrl

NM_023182.2

Chymotrypsin-like (Ctrl), mRNA.

4.04

1.01

−0.01

−3.52

Cuzd1

NM_008411.3

CUB and zona pellucida-like domains 1 (Cuzd1), mRNA.

1.70

0.72

−0.04

−1.25

Cygb

NM_030206.1

Cytoglobin (Cygb), mRNA.

0.12

−0.15

−0.51

−1.28

EG386551

NM_001003664.1

Predicted gene, EG386551 (EG386551), mRNA.

4.43

1.48

0.28

−3.41

EG436523

NM_001038997.1

Predicted gene, EG436523 (EG436523), mRNA.

3.28

1.50

0.15

−1.97

Ela1

NM_033612.1

Elastase 1, pancreatic (Ela1), mRNA.

2.04

0.61

0.21

−0.87

Ela2a

NM_007919.2

Elastase 2A (Ela2a), mRNA.

5.52

1.08

0.60

−6.00

Ela3b

NM_026419.1

 

4.62

1.22

0.04

−4.12

Golga2

NM_133852.2

Golgi autoantigen, golgin subfamily a, 2 (Golga2), transcript variant 1, mRNA.

1.21

0.03

−0.59

−0.91

Gp2

NM_025989.1

Glycoprotein 2 (zymogen granule membrane) (Gp2), mRNA.

3.78

0.91

−0.15

−2.07

Hamp2

NM_183257.1

Hepcidin antimicrobial peptide 2 (Hamp2), mRNA.

1.00

1.00

−0.29

−0.53

LOC100040233

XM_001474605.1

Predicted: similar to trypsinogen 15 (LOC100040233), mRNA.

3.23

1.27

0.04

−2.06

LOC100047162

XM_001477552.1

Predicted: similar to immunoglobulin kappa-chain (LOC100047162), mRNA.

0.62

0.51

−0.09

−1.40

LOC272683

XM_195289.1

 

0.32

0.07

−0.36

−1.03

LOC636875

XM_992953.1

Predicted: similar to Ig kappa chain V-V region L7 precursor (LOC636875), mRNA.

3.00

−0.33

0.16

−1.15

LOC636944

XM_912513.1

Predicted: similar to Ig kappa chain V-V region K2 precursor (LOC636944), mRNA.

1.04

0.69

0.24

−0.14

LOC669053

XM_972773.1

Predicted: similar to Ig kappa chain V-V region MPC11 precursor (LOC669053), mRNA.

0.30

0.62

−0.96

−1.42

LOC674114

XM_975388.1

Predicted: similar to Ig heavy chain V region 5-84 precursor (LOC674114), mRNA.

1.15

0.14

0.26

0.04

Pdia2

NM_001081070.1

Protein disulfide isomerase associated 2 (Pdia2), mRNA.

2.89

0.81

0.09

−1.97

Pitx2

NM_001042502.1

Paired-like homeodomain transcription factor 2 (Pitx2), transcript variant 3, mRNA.

0.48

0.56

−1.81

−2.20

Pitx2

NM_011098.3

Paired-like homeodomain transcription factor 2 (Pitx2), transcript variant 2, mRNA.

0.40

0.45

−1.17

−1.72

Pla2g1b

NM_011107.1

Phospholipase A2, group IB, pancreas (Pla2g1b), mRNA.

3.79

1.34

−0.02

−2.86

Pnlip

NM_026925.3

Pancreatic lipase (Pnlip), mRNA.

4.78

0.75

0.20

−4.79

Pnliprp1

NM_018874.2

Pancreatic lipase related protein 1 (Pnliprp1), mRNA.

4.79

0.58

1.00

−4.00

Ppap2b

NM_080555.2

Phosphatidic acid phosphatase type 2B (Ppap2b), mRNA.

−0.01

−0.13

−0.43

−1.12

Prss3

NM_011645.1

Protease, serine, 3 (Prss3), mRNA.

0.87

1.02

0.06

−0.25

Reg1

NM_009042.1

Regenerating islet-derived 1 (Reg1), mRNA.

4.03

0.59

−0.02

−3.41

Rnase1

NM_011271.2

Ribonuclease, RNase A family, 1 (pancreatic) (Rnase1), mRNA.

4.27

1.29

0.22

−3.58

Saa3

NM_011315.3

Serum amyloid A 3 (Saa3), mRNA.

0.24

−0.16

−0.46

−1.40

Serpina3n

NM_009252.2

Serine (or cysteine) peptidase inhibitor, clade A, member 3N (Serpina3n), mRNA.

0.19

−0.38

−0.35

−1.02

Tff2

NM_009363.3

Trefoil factor 2 (spasmolytic protein 1) (Tff2), mRNA.

2.84

0.81

0.15

−2.18

Try10

NM_001038996.1

Trypsin 10 (Try10), mRNA.

3.73

1.55

0.09

−2.84

Try4

NM_011646.5

Trypsin 4 (Try4), mRNA.

4.72

1.34

0.15

−3.67

  1. Log2 fold change of ≥1 or ≤−1 corresponds to a fold change of ≥2 or ≤−2, respectively, based on a comparison between high-fat diet- and normal diet-fed mice at each time point (P < 0.05)