Time-course microarray analysis for identifying candidate genes involved in obesity-associated pathological changes in the mouse colon

Table 5 Gene ontology biological pathway analysis of genes in cluster 4

GO term	Pop hits	No. of genes	Genes	P value	FDR
Proteolysis	1034	15	Prss3, Ela3b, Ctrb1, Cpa2, Try10, Ela2a, Ela1, EG436523, EG386551, 1810049H19Rik, LOC100040233, Ctrl, Try4, Cuzd1, Cpb1	<0.0001	<0.0001
Lipid catabolic process	134	5	Clps, Pla2g1b, Cel, Pnlip, Pnliprp1	<0.0001	<0.01
Digestion	26	3	Clps, Ctrb1, Pnlip	<0.01	0.059
Defense response	448	4	Saa3, Apoa4, Hamp2, Serpina3n	0.053	0.890
Acute-phase response	30	2	Saa3, Serpina3n	0.056	0.846

GO gene ontology, FDR false discovery rate using a Benjamini and Hochberg multiple testing correction, Pop Hits number of genes for a particular GO term, P value modified Fisher’s exact P value calculated by DAVID software

ISSN: 1865-3499