Fig. 2
Micronutrient correlation network visualizations of baseline in 36 overweight and obese men with mildly elevated CRP levels. Spearman correlation analysis was performed with all data measured after overnight fasting. The network represent all correlations >|0.5| in connection to the micronutrient nodes. The thickness of edges represents the strength of correlation, positive and negative correlations are presented as blue and red edges, respectively. Node size reflects the degree of centrality in the network. Centrality is a measure of the connectedness of a network node; it therefore reflects how many connects each node has to others. Activin A receptor type 1B (ACVR1B), aldo-keto reductase family 1, member A1 (AKR1A1), alanine aminotransferase (ALT), apolipoprotein C3 (APOC3), apolipoprotein H (APOH), ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide (ATP5B), bone morphogenetic protein 1 (BMP1), stearic acid (C18:0), vaccenic acid (C18:1), complement C1r subcomponent (C1R), complement component (C3), CD40 molecule (CD40), checkpoint kinase 1 (CHEK1), chemokine cxc motif ligand 8 (CXCL8), diglyceride (DG), family with sequence similarity 107 member 8 (DRR1), ephrin A5 (EFNA5), estrogen receptor 1 (ESR1), Fc receptor like 3 (FCRL3), homeostatic model assessment for insulin resistance (HOMA-IR), high sensitivity c-reactive protein (hsCRP), interleukin 1 receptor type 1 (IL1R1), interleukin 20 receptor subunit alpha (IL20RA), interleukin 34 (IL34), interleukin 5 (IL5), kallikrein related peptidase 8 (KLK8), kallikrein related peptidase 11 (KLK11), keratin 18 (KRT18), layilin (LAYN), leptin receptor (LEPR), leukocyte immunoglobulin like receptor B2 (LILRB2), leukotriene a4 hydrolase (LTA4H), mitogen activated protein kinase 11 (MAPK11), colony-stimulating factor 1 (macrophage) (M-CSF), matrix metallopeptidase 8 (MMP8), osteomodulin (OMD) plasminogen activator inhibitor 1 (PAI1), protein C (PROC), prostaglandin endoperoxide synthase 2 (PTGS2), peptide YY (PYY), serpin family A member 6 (SERPINA6), SH2 domain containing 1A (SH2D1A), secretory leukocyte peptidase inhibitor (SLPI), sortilin-related vps10 domain containing receptor 2 (SORCS2), tenascin C (TNC), tumor necrosis factor receptor superfamily member 10d (TNFRSF10D), tumor necrosis factor receptor superfamily member 19 (TNFRSF19), topoisomerase (DNA) 1 (TOP1), vascular endothelial growth factor A (VEGFA), X-ray repair complementing defective repair in Chinese hamster cell 6 (XRCC6)