Fig. 3
Micronutrient correlation network visualizations of NCT response in 36 overweight and obese men with mildly elevated CRP levels. Spearman correlation analysis was performed with all data measured with micronutrient AUCp or AUCn response data, i.e., NCT response. The networks represent all correlations >|0.4| in connection to the micronutrient nodes (AUCp = blue node, AUCn = red node). The thickness of edges represents the strength of correlation, positive and negative correlations are presented as blue and red edges, respectively. Node size reflects the degree of centrality in the network. Centrality is a measure of the connectedness of a network node, it therefore reflects how many connects each node has to others. Albumin (ALB), alkaline phosphatase, liver/bone/kidney (ALPL), annexin A1 (ANXA1), apolipoprotein A1 (APOA1), N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 (ASAH2), bone morphogenetic protein 7 (BMP7), bactericidal/permeability-increasing protein (BPI), palmitic acid (C16:0), margaric acid (C17:0), stearic acid (C18:0), vaccinic acid (C18:1), complement C1r subcomponent (C1R), complement component 3 (C3), C-C motif chemokine ligand 4 (CCL4), C-C motif chemokine ligand 25 (CCL25), CD33 molecule (CD33), creatine kinase m-type (CKM), chymase 1 (CMA1), collagen type VIII alpha 1 (COL8A1), chemokine cxc motif ligand 11 (CXCL11), endothelial cell specific molecule 1 (ESM1), growth differentiation factor 11 (GFD11), GDNF family receptor alpha (GFRA1), hydroxysteroid (17-beta) dehydrogenase 1 (HSD17B1), interferon lambda 1 (IFNL1), interleukin 8 (IL8), Inosine 5′ monophosphate dehydrogenase 1 (IMPDH1), inhibin beta A (INHBA), kallikrein related peptidase 13 (KLK13), matrix metallo peptidase 2 (MMP2) matrix metallo peptidase 16 (MMP16), pescadillo ribosomal biogenesis factor 1 (PES1), protein C (PROC), proteasome 26S subunit, non-ATPase 7 (PSMD7), pleiotrophin (PTN), peptide YY (PYY), serpin family E member 1 (SERPINE1), structure specific recognition protein 1 (SSSRP1), tumor necrosis factor receptor superfamily member 1b (TNFRSF1B), thyroid stimulating hormone beta (TSHB), thymic stromal lymphopoietin (TSLP)