Genes & Nutrition

Table 4 Association with anthropometric measures at 10 selected genetic variants in young people aged 10 to 18 years

From: Examining for an association between candidate gene polymorphisms in the metabolic syndrome components on excess weight and adiposity measures in youth: a cross-sectional study

			Log BMI (kg/m²)^a				Log BF %^b				Log waist circumference (cm)^b
SNP	MAF	TEST	ß coefficient	SE	95% CI	p value	ß coefficient	SE	95% CI	p value	ß coefficient	SE	95% CI	p value
rs699	T	ADD	0.007	0.003	0.000, 0.013	0.036	0.005	0.004	−0.003, 0.013	0.210	0.0008	0.000	−0.001, 0.002	0.365
rs3842570	D	ADD	−0.000	0.003	−0.006, 0.006	0.973	0.003	0.004	−0.005, 0.011	0.440	−0.0004	0.000	−0.002, 0.001	0.628
rs285	T	ADD	0.002	0.003	−0.003, 0.008	0.406	−0.002	0.004	−0.010, 0.005	0.577	−0.0000	0.000	−0.001, 0.001	0.994
rs2230806	A	ADD	0.003	0.003	−0.003, 0.010	0.286	−0.002	0.004	−0.010, 0.006	0.686	−0.0009	0.001	−0.002, 0.000	0.319
rs7903146	T	ADD	−0.001	0.003	−0.008, 0.006	0.851	0.002	0.005	−0.007, 0.011	0.653	−0.0003	0.001	−0.002, 0.001	0.772
rs1800849	T	ADD	−0.008	0.005	−0.017, 0.001	0.104	−0.005	0.006	−0.017, 0.006	0.373	−0.0045	0.001	−0.007, −0.001	0.001
rs1805097	A	ADD	−0.006	0.003	−0.013, −0.000	0.043	−0.005	0.004	−0.013, 0.003	0.200	0.0000	0.000	−0.001, 0.002	0.951
rs17817449	G	ADD	0.007	0.003	0.001, 0.014	0.031	−0.000	0.004	−0.009, 0.008	0.907	0.0011	0.001	−0.000, 0.003	0.287
rs708272	T	ADD	−0.013	0.003	−0.008, 0.005	0.672	−0.004	0.004	−0.012, 0.004	0.351	−0.0007	0.001	−0.002, 0.001	0.434
rs4340	D	ADD	−0.000	0.003	−0.006, 0.006	0.954	−0.001	0.004	−0.008, 0.007	0.877	−0.0009	0.000	−0.002, 0.000	0.316
GRS-3		ADD	0.020	0.007	0.006, 0.033	0.004	–	–	–	–	–	–	–	–

The significant p values (p < 0.05) are given in bold
MAF minor allele frequency calculated using the data from all the subjects in the analysis, ADD additive, CI confidence interval, GRS genetic risk score
^aAdjusted for age, sex, and pubertal maturation
^bAdjusted for age, sex, pubertal maturation, and BMI

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ISSN: 1865-3499

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