Skip to main content

Table 3 Overview of indexes related to insulin resistance, insulin secretion, and β cell function and their values in response to OGTT as compared to PFT that both contain 75 g of glucose in 20 healthy male subjects and 20 type 2 diabetic male subjects

From: Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge

Index Healthy T2D FDR p values
OGTT PhenFlex OGTT PhenFlex OGTT PhenFlex
DI 6.31 ± 3.4 24.63 ± 41.7 0.51 ± 0.2 1.55 ± 0.8 0 0
IGI 1.28 ± 0.6 3.83 ± 5.7 0.26 ± 0.1 0.91 ± 0.5 0 0.00005
Matsuda 5.83 ± 3.4 7.40 ± 6.0 2.13 ± 1.0 1.84 ± 0.7 0.00002 0
MISI −1.65 ± 1.1 −1.13 ± 1.2 −0.58 ± 1.2 −0.14 ± 0.3 0 0.00006
  1. Data are presented as mean ± SD. The column FDR p values shows the FDR corrected p-values after statistical evaluation of indexes in healthy vs T2D per index and per challenge test
  2. DI disposition index, IGI insulinogenic index, MISI muscle insulin sensitivity index