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Table 3 Overview of indexes related to insulin resistance, insulin secretion, and β cell function and their values in response to OGTT as compared to PFT that both contain 75 g of glucose in 20 healthy male subjects and 20 type 2 diabetic male subjects

From: Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge

Index

Healthy

T2D

FDR p values

OGTT

PhenFlex

OGTT

PhenFlex

OGTT

PhenFlex

DI

6.31 ± 3.4

24.63 ± 41.7

0.51 ± 0.2

1.55 ± 0.8

0

0

IGI

1.28 ± 0.6

3.83 ± 5.7

0.26 ± 0.1

0.91 ± 0.5

0

0.00005

Matsuda

5.83 ± 3.4

7.40 ± 6.0

2.13 ± 1.0

1.84 ± 0.7

0.00002

0

MISI

−1.65 ± 1.1

−1.13 ± 1.2

−0.58 ± 1.2

−0.14 ± 0.3

0

0.00006

  1. Data are presented as mean ± SD. The column FDR p values shows the FDR corrected p-values after statistical evaluation of indexes in healthy vs T2D per index and per challenge test
  2. DI disposition index, IGI insulinogenic index, MISI muscle insulin sensitivity index
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Genes & Nutrition

ISSN: 1865-3499

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