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Table 2 Significant eQTL from positively selected cofactor transporter SNPs

From: Ancestors’ dietary patterns and environments could drive positive selection in genes involved in micronutrient metabolism—the case of cofactor transporters

PC SNP Gene Official gene name Tissue Cofactors Effect size p value
3 rs1471476 SLC25A26 Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 26 Heart—left ventricle SAH − 0.49 1.4E−06
3 rs17044224 SLC25A26 Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 26 Adipose—subcutaneous SAH − 0.32 4.9E−05
3 rs17044224 SLC25A26 Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 26 Heart—left Ventricle SAH − 0.5 5.0E−07
5 rs10485588 SLC24A3 Solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 Whole blood K, Ca 0.74 1.9E−08
5 rs16830593 CACNB4 Calcium Channel Voltage-Dependent Subunit Beta 4 Skin—sun exposed (lower leg) Ca − 0.82 6.6E−05
  1. From GTeX eQTL database
  2. Ca calcium, K potassium, SAH S-Adenosyl-l-homocysteine, PC principal component