Genetic polymorphisms of antioxidant enzymes CAT and SOD affect the outcome of clinical, biochemical, and anthropometric variables in people with obesity under a dietary intervention

Table 1 Effect of the 3-month dietary intervention on biochemical, clinical, and anthropometric variables on participants

Variables	Pre-intervention (n = 92)	Post-intervention (n = 92)	p value
Weight (kg)	91.9 ± 18.3 84.8	86.4 ± 15 84.4	< 0.031^a
BMI (kg/m²)	34.9 ± 4.4 33.7	31.9 ± 4.25 30.4	< 0.001^a
EI (Kcal/day)	1978 ± 326 1978	1926 ± 316 1840	0.320
Waist (cm)	96.5 ± 11.3 95.3	92.2 ± 10.2 92.3	< 0.001^b
WHR	0.79 ± 0.14 0.81	0.80 ± 0.13 0.78	0.960
Body fat (%)	44.5 ± 7.6 42.8	40.8 ± 8.4 41.8	0.100
Visceral fat (cm²)	173 ± 47,147.9	157 ± 49,142.9	0.100
SBP (mgHg)	124 ± 9.7120	119 ± 12.5121	< 0.001^a
DBP (mgHg)	86.1 ± 10.3 84	76.5 ± 7.9 76.5	< 0.001^a
TBARS (mg/dl)	1.39 ± 0.57 1.31	1.03 ± 0.43 1.07	< 0.001^a
Glucose (mg/dl)	123 ± 66.3101	108 ± 26.8 95.9	< 0.001^a
Triglycerides (mg/dl)	154 ± 38.3156	151 ± 57.5150	0.003^a
Total cholesterol (mg/dl)	177 ± 44.8163	154 ± 36.5152	< 0.001^a
HDL-C (mg/dl)	42.4 ± 12.7 43	43.6 ± 12.2 43	0.400
LDL-C (mg/dl)	119 ± 48.1115.3	94.9 ± 35.7 88.4	< 0.001^a
Atherogenic index	4.52 ± 1.73 4.19	3.96 ± 1.49 3.40	0.028^a

Data show: mean ± SD median. BMI body mass index, EI daily energy intake, WHR waist–hip ratio, SBP systolic blood pressure, DBP diastolic blood pressure, TBARS thiobarbituric acid reactive substances, HDL-C high-density lipoprotein, LDL-C low-density lipoprotein
^aWilcoxon signed-ranks test was used to compare groups
^bPaired t test was used to compare groups

ISSN: 1865-3499