Skip to main content

Table 3 FTO genotype and measures of body weight stratified by ethnicity and protein intake

From: FTO genotype, dietary protein intake, and body weight in a multiethnic population of young adults: a cross-sectional study

 

Low protein (≤ median intake)a

High protein (> median intake)a

 

rs1558902 genotype

 

rs1558902 genotype

 

Interaction

TT

TA

AA

p b

TT

TA

AA

p b

p c

Caucasian

 Subjects (n)

115

197

68

 

141

170

68

  

 Body mass index (kg/m2)

22.4 ± 0.3d

23.1 ± 0.2

23.1 ± 0.4

0.2

23.3 ± 0.3

24.1 ± 0.3

23.7 ± 0.4

0.17

0.95

 Waist circumference (cm)

73.6 ± 0.7

76.2 ± 0.6

75.4 ± 1.1

0.07

75.5 ± 0.7

76.6 ± 0.8

75.9 ± 1.0

0.17

0.99

East Asian

 Subjects (n)

215

55

9

 

207

70

2

  

 Body mass index (kg/m2)

21.5 ± 0.2c

22.5 ± 0.3b

25.0 ± 1.3a

< 0.0001

21.8 ± 0.2

21.5 ± 0.3

22.4 ± 1.9

0.58

0.01

 Waist circumference (cm)

70.6 ± 0.5b

72.0 ± 0.9b

78.9 ± 3.4a

0.0006

71.4 ± 0.5

71.0 ± 0.8

68.1 ± 1.3

0.34

0.007

South Asian

 Subjects (n)

42

40

5

 

42

37

8

  

 Body mass index (kg/m2)

23.8 ± 0.7

23.4 ± 0.7

24.4 ± 2.3

0.83

23.5 ± 0.5

23.9 ± 0.8

25.0 ± 2.7

0.86

0.86

 Waist circumference (cm)

76.8 ± 1.7

74.4 ± 1.8

76.3 ± 5.2

0.75

76.0 ± 1.3

75.9 ± 2.5

77.8 ± 5.4

0.98

0.76

  1. Groups without a common letter differ after a Tukey-Kramer post hoc test (p<0.05)
  2. aLow and high protein intakes determined using ethnicity-specific medians: Caucasians (17% energy intake), East Asians (18% energy intake), South Asians (17% energy intake)
  3. bDetermined using GLMs adjusted for age and sex
  4. cInteractions between rs1558902 genotype and energy-adjusted protein intake on markers of body mass determined using GLMs adjusted for age and sex
  5. dMean ± SE (all such values)
Back to article page

Genes & Nutrition

ISSN: 1865-3499

Contact us