Skip to main content

Table 2 Evaluation of cell viability and growth-inhibition rates in DHA-treated cells

From: Omega-3 fatty acid DHA modulates p53, survivin, and microRNA-16-1 expression in KRAS-mutant colorectal cancer stem-like cells

 

Cell viability (% control)

Growth inhibition (% control)

DHA (μM)

48 h

24 h

48 h

72 h

100

*86.5 ± 0.7

**54.7 ± 7.5

**73.3 ± 2.9

**63.3 ± 4

150

*78.5 ± 2.1

**50 ± 9.8

**70.3 ± 0.6

**83 ± 5.6

200

**44 ± 1.5

**59.7 ± 6.5

**75.8 ± 2.1

**97.7 ± 1.5

  1. 5 × 103 HCT-116 cells per well were treated for 24, 48, and 72 h with various concentrations of DHA after which, growth inhibition rates were measured. 5 × 105 cells per well were treated for 48 h with indicated concentrations of DHA after which cell viability was determined using trypan blue dye exclusion. Experiments were repeated twice using triplicate assays and the results were presented as the mean ± SD
  2. *P < 0.05 and **P < 0.01 vs. untreated cells
Back to article page

Genes & Nutrition

ISSN: 1865-3499

Contact us