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Table 1 Participant characteristics

From: Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study

Variable

Baseline

Change during weight loss

n

Mean ± sd

n

Mean ± sd

Gender (M/F)

769

263/506

Age (years)

769

41.28 ± 6.22

BMI (kg/m2)

762

34.54 ± 4.88

638

3.80 ± 1.12

Total cholesterol (mmol/l)

714

4.89 ± 1.01

620

0.66 ± 0.76

HDL-C (mmol/l)

716

1.20 ± 0.33

624

0.08 ± 0.23

LDL-C (mmol/l)

711

3.07 ± 0.88

616

0.45 ± 0.64

TG (mmol/l)

705

1.35 ± 0.65

611

0.31 ± 0.58

FFA (μmol/l)

630

654.9 ± 333.2

545

− 55.3 ± 368.4

Glucose (mmol/l)

701

5.12 ± 0.74

606

0.29 ± 0.60

Insulin (μIU/ml)

683

11.48 ± 8.57

541

3.89 ± 5.60

CRP (mg/l)

698

4.30 ± 3.90

594

1.05 ± 2.55

ANGPTL3 (RFU)

567

349.2 ± 122.0

539

1.74 ± 85.8

ALT (RFU)

594

5493.6 ± 2399.9

543

6.55 ± 204.3

AST (RFU)

594

7867.6 ± 2581.6

543

− 0.93 ± 218.5

Adiponectin (RFU)

594

1430.8 ± 555.4

543

− 0.87 ± 196.7

Fetuin A (RFU)

594

1029.2 ± 190.7

543

− 4.66 ± 213.7

Fetuin B (RFU)

594

4026.6 ± 1342.0

543

2.66 ± 128.9

CK-18 (RFU)

594

222.0 ± 916.1

543

− 4.08 ± 123.2

  1. ALT alanine aminotransferase, ANGPTL3 angiopoietin-like protein 3, AST aspartate aminotransferase, BMI body mass index, CK-18 cytokeratin 18, CRP C-reactive protein, FFA free fatty acids, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, sd standard deviation, TG triglycerides