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Table 2 Plasma ANGPTL3 and association with BMI and lipid profile

From: Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study

Variable

Baseline

 

Weight loss period

β (95%CI)

p

β (95%CI)

p

BMI (kg/m2)

0.00 (− 0.44;0.45)

0.986

6.39 (− 0.18;13.0)

0.056

Total cholesterol (mmol/l)

0.45 (− 1.75;2.69)

0.691

6.29 (− 3.11;15.7)

0.189

HDL-C (mmol/l)

− 3.62 (− 10.4;3.67)

0.322

− 21.2 (− 55.30;12.8)

0.221

LDL-C (mmol/l)

− 0.15 (− 2.60;2.37)

0.906

4.81 (− 6.17;15.8)

0.390

TG (mmol/l)

3.21 (− 0.34;6.89)

0.077

15.7 (2.15;29.2)

0.023

FFA (μmol/l)

0.01 (− 0.00;0.01)

0.134

0.00 (− 0.03;0.02)

0.728

Glucose (mmol/l)

− 0.35 (− 3.67;3.08)

0.839

− 8.13 (− 20.36;4.10)

0.193

Insulin (μIU/ml)

0.10 (− 0.18;0.37)

0.485

1.54 (0.06;3.02)

0.042

CRP (mg/l)

0.28 (− 0.35;0.91)

0.383

1.89 (− 0.89;4.66)

0.183

  1. Coefficient (β), corresponding 95% confidence intervals, and associated p value from a linear regression are provided. Data are presented as back-transformed β-coefficients in percent with regard to results at baseline. Thus, an increase in ANGPTL3 of 1 RFU results in β (95%CI) percent change of the given variable. The regression models were adjusted for center, age, gender, and BMI. Models with data from the weight loss period were adjusted for the change in BMI due to the weight loss
  2. CI Confidence interval, CRP C-reactive protein, FFA free fatty acids, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglycerides