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Table 1 Means (and standard deviations) or percentage distribution for baseline characteristics across tertiles of a weighted genetic risk score for type 2 diabetes and across categories of a diet risk score in 15,380 women and 9689 men from the Malmö Diet and Cancer Study

From: Dietary and genetic risk scores and incidence of type 2 diabetes

  

All

Tertile of genetic risk score

 

Women

Tertile of genetic risk score

 

Men

Tertile of genetic risk score

 
 

n

1

2

3

P trend*

1

2

3

P trend*

1

2

3

P trend*

Age (years)

25,069

58.3 (7.8)

58.2 (7.6)

58.2 (7.7)

0.32

57.3 (8.0)

57.3 (7.9)

57.3 (8.0)

0.86

59.5 (7.2)

59.0 (7.1)

59.1 (7.1)

0.04

BMI

25,035

25.7 (4.0)

25.7 (3.9)

25.6 (3.8)

0.12

25.3 (4.2)

25.4 (4.2)

25.3 4.0)

0.48

26.2 (3.5)

26.2 (3.4)

26.0 (3.4)

0.046

Fasting blood glucose (mmol/L)

4860

4.90 (0.6)

5.00 (0.7)

5.05 (0.8)

< 0.001

4.78 (0.5)

4.88 (0.6)

4.94 (0.7)

< 0.001

5.06 (0.6)

5.17 (0.8)

5.21 (1.0)

0.001

Fasting plasma insulin (mIU/L)

4819

7.8 (8.9)

7.7 (8.1)

7.7 (6.1)

0.89

7.3 (8.3)

7.0 (5.0)

7.2 (4.8)

0.75

8.5 (9.5)

8.7 (11.3)

8.6 (7.4)

0.93

HOMA-IR†

4571

1.60 (1.43)

1.59 (1.12)

1.61 (1.13)

0.76†

1.49 (1.54)

1.47 (1.04)

1.49 (0.96)

0.66†

1.76 (1.23)

1.77 (1.21)

1.80 (1.32)

0.29†

Alcohol intake (g/day) ‡

23,551

11.6 (12.8)

11.5 (12.9)

11.3 (12.3)

0.11

8.5 (8.9)

8.3 (8.6)

8.3 (8.7)

0.21

16.4 (16.0)

16.4 (16.4)

15.9 (15.3)

0.26

Processed meat (g/day)

25,069

38 (30)

38 (30)

38 (30)

0.61

31 (23)

31 (23)

31 (23)

0.57

51 (35)

49 (36)

50 (36)

0.68

Sugar-sweetened beverages (g/day)

25,069

76 (145)

78 (150)

77 (145)

0.64

67 (125)

65 (121)

66 (127)

0.83

91 (171)

99 (187)

95 (170)

0.42

Whole grain (portions/day)

25,069

1.0 (1.0)

1.0 (1.0)

1.0 (1.0)

0.93

0.9 (0.9)

0.9 (0.9)

0.9 (0.9)

0.65

1.0 (1.2)

1.1 (1.2)

1.1 (1.2)

0.58

Coffee (g/day)

25,069

520 (390)

530 (400)

510 (400)

0.77

510 (380)

520 (390)

510 (390)

0.87

530 (400)

540 (420)

530 (410)

0.77

     

P value

   

P value

   

P value

Smoking (ever) (%)

25,059

62.4

61.7

61.1

0.22

56.7

55.6

54.9

0.17

71.3

71.3

71.4

0.99

Leisure time physical activity, high (%)§

24,913

18.9

20.6

20.2

0.02

19.4

20.1

20.2

0.58

18.2

21.4

20.3

0.01

Education (> 10 years) (%)

25,008

32.0

32.7

31.5

0.25

31.1

30.5

30.3

0.68

33.3

36.3

33.3

0.02

  

Diet risk score

 

Diet risk score

 

Diet risk score

 
 

n

Low

Mid

High

P trend*

Low

Mid

High

P trend*

Low

Mid

High

P trend*

n

 

5699

15,188

4182

 

3767

9205

2408

 

1932

5983

1774

 

Age (years)

25,069

57.6 (7.4)

58.4 (7.7)

58.7 (8.0)

< 0.001

56.6 (7.5)

57.4 (8.0)

57.8 (8.4)

< 0.001

58.6 (6.8)

59.3 (7.1)

59.6 (7.2)

< 0.001

BMI

25,035

25.4 (3.8)

25.6 (3.9)

26.0 (4.0)

< 0.001

25.0 (3.9)

25.3 (4.2)

25.7 (4.2)

< 0.001

26.1 (3.3)

26.1 (3.4))

26.6 (3.5)

< 0.001

Fasting blood glucose (mmol/L)

4860

4.94 (0.7)

4.98 (0.7)

5.07 (0.9)

< 0.001

4.82 (0.5)

4.89 (0.6)

4.92 (0.7)

0.005

5.13 (0.9)

5.12 (0.7)

5.28 (1.0)

0.03

Fasting plasma insulin (mIU/L)

4819

7.4 (7.3)

7.7 (8.0)

8.7 (7.6)

0.001

7.0 (8.1)

7.1 (5.4)

7.7 (4.8)

0.12

7.8 (5.4)

8.6 (10.6)

10.0 (9.8)

0.002

HOMA-IR†

4571

1.52 (1.49)

1.58 (1.07)

1.81 (1.35)

< 0.001

1.46 (1.68)

1.46 (0.91)

1.66 (1.14)

< 0.001

1.61 (1.04)

1.77 (1.23)

2.03 (1.54)

< 0.001

Alcohol intake (g/day)‡

23,551

11.5 (12.0)

11.4 (12.6)

11.7 (13.8)

0.53

8.6 (8.5)

8.4 (8.7)

7.8 (8.9)

0.007

15.9 (15.7)

16.0 (15.7)

17.4 (16.8)

0.009

Processed meat (g/day)

25,069

22 (21)

40 (30)

55 (31)

< 0.001

18 (16)

32 (23)

46 (24)

< 0.001

28 (26)

51 (36)

69 (36)

< 0.001

Sugar-sweetened beverages (g/day)

25,069

18 (70)

70 (140)

170 (200)

< 0.001

12 (52)

66 (124)

150 (156)

< 0.001

25 (91)

84 (161)

209 (235)

< 0.001

Whole grain (portions/day)

25,069

1.6 (1.2)

0.9 (0.9)

0.4 (0.5)

< 0.001

1.5 (0.9)

0.8 (0.8)

0.4 (0.4)

< 0.001

1.9 (1.4)

1.0 (1.1)

0.4 (0.5)

< 0.001

Coffee (g/day)

25,069

700 (410)

510 (390)

310 (260)

< 0.001

680 (400)

490 (370)

310 (270)

< 0.001

735 (430)

530 (410)

320 (260)

< 0.001

     

P value

   

P value

   

P value

Smoking (ever) (%)

25,059

65.2

61.3

58.5

< 0.001

60.7

55.0

50.6

< 0.001

74.1

71.1

69.3

< 0.004

Leisure time Physical Activity, high (%)§

24,913

22.3

19.3

18.9

< 0.001

22.9

19.1

18.1

< 0.001

21.2

19.5

19.8

0.30

Education (> 10 years) (%)

25,008

37.7

31.6

26.3

< 0.001

35.7

30.4

23.6

< 0.001

41.8

33.3

29.9

< 0.001

  1. *Adjusted for age and sex when applicable
  2. †P value for ln transformed variables
  3. ‡Among those reporting that they consumed alcohol during the year before baseline examinations
  4. §Highest quintile of leisure time physical activity