Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: a cross-sectional study in healthy subjects

Table 4 Differentially expressed genes between subjects in the highest and lowest plasma n-3 tertile

Gene	Highest tertile (n 18)	Lowest tertile (n 18)	Mean Difference	P
SNX5	8.53 ± 0.13	8.43 ± 0.14	0.10	0.029
AMPD3	6.94 ± 0.06	6.88 ± 0.06	0.06	0.012
LCAT	6.93 ± 0.07	6.99 ± 0.07	− 0.06	0.013
RORA	7.11 ± 0.13	7.21 ± 0.10	− 0.10	0.018
FAM13A	7.33 ± 0.14	7.43 ± 0.15	− 0.10	0.049
UBE2L3*	7.16 ± 0.16	7.28 ± 0.17	− 0.12	0.035
ANKRA2	9.10 ± 0.20	9.25 ± 0.17	− 0.15	0.017
THBS1	7.29 ± 0.32	7.62 ± 0.43	− 0.32	0.016

Expression of genes is given as mRNA level. Values are presented as mean ± SD and are log2 transformed. Differences between tertiles were analyzed using the independent samples t test. P values < 0.05 were considered significant
*Genes differentially expressed between subjects in the highest and lowest n-3 tertile and between subjects in the highest and lowest SFA to PUFA ratio tertile. The genes presented in italics are expressed by more than one probe (shown in Additional file 3: Table S3). The probe with lowest p-value is shown in Table 4

ISSN: 1865-3499