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Correction to: Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: a cross-sectional study in healthy subjects

  • 1,
  • 1, 2,
  • 1,
  • 3,
  • 3 and
  • 1Email author
Genes & Nutrition201813:16

https://doi.org/10.1186/s12263-018-0604-8

Received: 20 June 2018

Accepted: 20 June 2018

Published: 5 July 2018

The original article was published in Genes & Nutrition 2018 13:9

Correction

Unfortunately, after publication of this article [1], it was noticed that some corrections to Table 2 were not carried out. The corrected Table 2 can be seen below and the original article has also been updated to reflect this.
Table 2

Characteristics and plasma fatty acid profile of subjects in the highest and lowest tertiles

 

n-6 level

n-3 level

SFA/PUFA ratio

Highest tertile

Lowest tertile

P

Highest tertile

Lowest tertile

P

Highest tertile

Lowest tertile

P

(n 18)

(n 18)

(n 18)

(n 18)

(n 18)

(n 18)

Male/female

5/13

5/13

 

3/15

5/13

 

5/13

6/12

 

Age (years)

25 (23–33)

25 (21–29)

0.31

25 (21–31)

24 (21–28)

0.80

25 (22–29)

28 (23.0–32.8)

0.38

BMI (kg/m2)

22.5 ± 2.9

22.6 ± 2.6

0.94

22.2 ± 2

22.7 ± 3.3

0.57

23.3 ± 2.7

22.6 ± 2.6

0.41

Total-C (mmol/l)

4.9 ± 0.9

4.7 ± 1.1

0.65

4.9 ± 1

4.9 ± 1

0.96

4.7 ± 0.8

5.0 ± 0.9

0.25

LDL-C (mmol/l)

2.7 ± 0.8

2.6 ± 0.9

0.79

2.6 ± 0.9

2.8 ± 0.6

0.71

2.5 ± 0.6

2.8 ± 0.9

0.16

HDL-C (mmol/l)

1.6 ± 0.4

1.4 ± 0.3

0.15

1.6 ± 0.3

1.4 ± 0.4

0.28

1.5 ± 0.4

1.6 ± 0.3

0.74

TG (mmol/l)

0.8 (0.6–0.9)

1.2 (0.9–1.7)

0.01

0.8 (0.6–1.1)

1.0 (0.7–1.2)

0.30

1.1 (0.8–1.6)

0.8 (0.6–0.9)

0.01

Lymphocytes (%)

38.4 ± 6.8

43.0 ± 8.5

0.08

42.2 ± 10.0

37.6 ± 4

0.09

42.1 ± 8.7

37.4 ± 8.4

0.11

Monocytes (%)

8.5 ± 1.8

8.1 ± 1.9

0.49

8.1 ± 1.7

8.6 ± 2.3

0.42

8.8 ± 2.2

8.48 ± 2.0

0.71

Plasma level of fatty (wt%)

         

Total SFA

29.4 (28.8–30.5)

32.1 (31.1–33.2)

< 0.01

30.7 (29.3–32.3)

30.8 (29.8–31.8)

0.78

32.6 (31.5–33.2)

29.1 (28.7–29.5)

< 0.01

Myristic acid (14:0)

0.6 (0.6–1.0)

1.0 (0.8–1.2)

< 0.01

0.8 (0.6–1.1)

0.9 (0.7–1.1)

0.57

1.1 (0.9–1.2)

0.6 (0.6–0.9)

< 0.01

Palmitic acid (16:0)

20.5 (20.2–21.6)

23.4 (21.4–24.2)

< 0.01

20.9 (20.4–23.7)

21.5 (20.9–22.6)

0.39

23.9 (21.8–24.5)

20.4 (20.2–20.7)

< 0.01

Stearic acid (18:0)

8.1 ± 0.7

8.1 ± 1.1

0.86

8.2 ± 1.1

8.0 ± 1.0

0.65

8.0 ± 1.1

7.7 ± 0.8

0.37

Total n-6

38.6 ± 1.3

30.3 ± 2.9

< 0.01

31.0 ± 4.0

31.5 ± 4.5

0.74

30.8 ± 3.4

38.0 ± 2.0

< 0.01

LA (18:2n-6)

32.3 ± 1.6

24.9 ± 2.5

< 0.01

27.8 ± 3.8

29.2 ± 4.1

0.29

24.8 ± 2.5

31.8 ± 2.1

< 0.01

AA (20:4n-6)

6.2 ± 1.1

5.4 ± 0.9

0.02

5.8 ± 0.7

6.2 ± 1.2

0.32

5.9 ± 1.3

6.2 ± 1. 1

0.58

Total n-3

5.8 ± 2.5

7.0 ± 2.3

0.12

9.0 ± 0.9

3.6 ± 0.49

< 0.01

6.1 ± 2.5

6.8 ± 2.4

0.44

ALA (18:3n- 3)

0.5 (0.5–0.6)

0.5 (0.4–0.6)

0.46

0.5 (0.5–0.6)

0.5 (0.5–0.6)

0.79

0.5 (0.5–0.6)

0.5 (0.5–0.5)

0.95

EPA (20:5n-3)

1.7 (0.6–2.3)

2.4 (1.8–2.9)

0.14

3.2 (2.8–3.7)

0.6 (0.5–0.6)

< 0.01

2.0 (0.7–2.6)

2.2 (1.3–3.2)

0.46

DPA (22:5n-3)

0.6 ± 0.1

0.7 ± 0.2

0.26

0.8 ± 0.1

0.5 ± 0.1

< 0.01

0.6 ± 0.2

0.6 ± 0.1

0.80

DHA (22:6n-3)

3.0 (1.9–4.1)

4.0 (3.1–4.1)

0.14

4.3 (4.1–4.7)

1.9 (1.8–2.1)

< 0.01

3.5 (2.0–4.1)

3.3 (2.8–4.3)

0.48

Total PUFA

43.8 (42.1–47.3)

38.6 (35.8–39.7)

< 0.01

42.2 (39.5–46.7)

40.4 (37.7–41.5)

0.05

37.8 (35.8–39.1)

44.6 (43.1–47.3)

< 0.01

SFA to PUFA ratio

0.7 (0.6–0.7)

0.8 (0.8–0.9)

< 0.01

0.7 (0.6–0.8)

0.8 (0.7–0.8)

0.13

0.9 (0.8–0.9)

0.7 (0.6–0.7)

< 0.01

Lymphocytes and monocytes are given as percentage of total white cell count. Differences between tertiles were analyzed using the independent samples t test when normally distributed or the Mann-Whitney U test when not normally distributed. P values < 0.05 were considered significant. Values are presented as mean ± SD or medians and 25th–75th percentile

BMI body mass index, Total-C total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, SFA saturated fatty acid, LA linoleic acid, AA arachidonic acid, ALA alpha-linolenic acid, EPA eicosapentaenoic acid, DPA docosapentaenoic acid, DHA docosahexaenoic acid, PUFA polyunsaturated fatty acid

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Department of Nutrition, Institute for Basic Medical Sciences, University of Oslo, Oslo, Norway
(2)
Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway
(3)
Department of Health, Nutrition and Management, Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, Oslo, Norway

Reference

  1. Larsen SV, Holven KB, Ottestad I, Dagsland KN, Myhrstad MCW, Ulven SM. Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells: a cross-sectional study in healthy subjects. Genes Nutr. 2018;13:9. https://doi.org/10.1186/s12263-018-0600-z.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s) 2018

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