Skip to main content
Fig. 1 | Genes & Nutrition

Fig. 1

From: Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans

Fig. 1

Knockdown of cbs-1 and metr-1 via RNAi increase Hcy level and paralysis rate in CL2006. Hcy concentration was determined with the Human Hcy-ELISA Kit 48 h after nematodes had reached the young adult stage (a). At the same, stage paralysis in CL2006 was assessed subsequent to a heat-shock for 1.5 h at 35 °C by tapping the nematodes with a bent platinum wire and subsequent scoring of their moving ability (b). ***p < 0.001 versus the vector control

Back to article page