Fig. 2From: Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African populationImpact of weighted genetic risk score (wGRSz) on BMI at 18 years via adolescent conditional relative weight gain. Notes: Path a is the direct effect of the wGRSz on mediator (adolescent weight gain). Path b is the mediator’s effect on the outcome (BMI at 18 years) eliminating the effect of wGRSz. The total effect of wGRSz on BMI at 18 years is c = c’ + a × b, where a × b is the indirect effect of wGRSz on BMI at 18 years via adolescent weight gainBack to article page