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Fig. 2 | Genes & Nutrition

Fig. 2

From: Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African population

Fig. 2

Impact of weighted genetic risk score (wGRSz) on BMI at 18 years via adolescent conditional relative weight gain. Notes: Path a is the direct effect of the wGRSz on mediator (adolescent weight gain). Path b is the mediator’s effect on the outcome (BMI at 18 years) eliminating the effect of wGRSz. The total effect of wGRSz on BMI at 18 years is c = c’ + a × b, where a × b is the indirect effect of wGRSz on BMI at 18 years via adolescent weight gain

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