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Table 2 Intraclass correlation coefficients between intrafamilial pairs and heritability of 25-hydroxyvitamin D

From: Genetic influence on serum 25-hydroxyvitamin D concentration in Korean men: a cross-sectional study

 

Intraclass correlation coefficients (95% CI)

H2 (SE)

VAR (%)

Models

Between MZ twin pairs (n = 146 pairs)

Between sibling pairs (n = 147 pairs)

Between father-son pairs (n = 266 pairs)

Age-adjusted

0.61 (0.54–0.68)

0.43 (0.34–0.51)

0.31 (0.25–0.38)

0.58 (0.09)

3.7

Model 1a

0.54 (0.45–0.61)

0.34 (0.25–0.43)

0.27 (0.20–0.34)

0.52 (0.05)

16.2

Model 2b

0.53 (0.44–0.61)

0.34 (0.24–0.43)

0.28 (0.20–0.34)

0.51 (0.09)

16.6

  1. CI confidence interval, MZ monozygotic, H2 (SE) heritability (standard error), VAR proportion of variance explained by covariates
  2. aIn model 1, physical activity, multivitamin intake, and season were additionally adjusted from age-adjusted model
  3. bIn model 2, smoking status and alcohol consumption were further added to model 1
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Genes & Nutrition

ISSN: 1865-3499

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