Genetic influence on serum 25-hydroxyvitamin D concentration in Korean men: a cross-sectional study

Genes & Nutrition

Table 3 Intraclass correlation coefficients between intrafamilial pairs and heritability of 25-hydroxyvitamin D, after exclusion of participants who reported on multivitamin usage

	Intraclass correlation coefficients (95% CI)			H² (SE)	VAR (%)
Models	Between MZ twin pairs (n = 98 pairs)	Between sibling pairs (n = 115 pairs)	Between father-son pairs (n = 167 pairs)	H² (SE)	VAR (%)
Age-adjusted	0.57 (0.47–0.66)	0.46 (0.36–0.55)	0.35 (0.27–0.43)	0.44 (0.10)	4.0
Model 1^a	0.51 (0.40–0.61)	0.37 (0.27–0.47)	0.32 (0.23–0.40)	0.39 (0.10)	15.8
Model 2^b	0.51 (0.40–0.61)	0.36 (0.26–0.46)	0.32 (0.23–0.40)	0.40 (0.10)	15.5

CI confidence interval, MZ monozygotic, H² (SE) heritability (standard error), VAR proportion of variance explained by covariates
^a In model 1, physical activity and season were additionally adjusted from age-adjusted model
^b In model 2, smoking status and alcohol consumption were further added to model 1

ISSN: 1865-3499