Skip to main content

Table 2 List of reported candidate biomarkers for tuber intakes

From: Biomarkers of tuber intake

Dietary factor

Study design

Subjects

Analytical method

Sample type

Discriminating metabolites /Candidate biomarkers

Identifier

Primary reference(s)

Potato

Human meal study

34

Radioimmunoassay

Plasma

Solanidine

HMDB0003236

[27]

Potato products (i.e., French fries, boiled, baked or mashed potato with or without skin)

Observational study

57

Radioimmunoassay

Serum

Solanidine

HMDB0003236

[28]

Parallel human dietary study

2

Unpeeled potato

Parallel human dietary study

43

Radioimmunoassay

Serum (1 collection before lunch); Saliva (1 collection, eirher immediately before or after blood sampling)

Solanidine

HMDB0003236

[104]

Total potato alkaloids (α-solanine, α-chaconine and aglycone solanidine)

HMDB0003236

HMDB0039353

HMDB0003236

Mashed peeled potatoes

Human meal study

7

HPLC

Serum (prior and 0–25 h postdose)

Solanidine

HMDB0003236

[29]

α-Solanine

HMDB0034202

α-Chaconine

HMDB0039353

Solution with low glycoalkaloid dose; mashed potato with high glycoalkaloid dose

Human meal study

14

HPLC

Serum (prior and 0–96 h postdose)

α-Solanine

HMDB0034202

[30]

α-Chaconine

HMDB0039353

Sweet potato (beverage with an extract of anthocyanin)

Human meal study

6

liquid chromatography/mass spectrometry (LC/MS)

Plasma and urine (prior and 30–120 min and 24 h postdose)

Pn 3-Caf·sop-5-glc

Not in HMDB

[73]

Cy 3-Caf·sop-5-glc

Not in HMDB

Sweet potato (beverage with an extract of anthocyanin)

Human meal study

87

LC-ESI-MS/MS

Urine (2 h postdose)

Pn 3-Caf·sop-5-glc

Not in HMDB

[74]

Cassava

Observational study

175

Spectrophotometry

Urine

Linamarin

HMDB0033699

[105]

Cassava (Stiff porridge)

Human meal study

22

Spectrophotometry

Urine

Linamarin

HMDB0033699

[97]

Cassava (Stiff porridge made from short-soaked roots of bitter cassava varieties)

Observational study

173

Spectrophotometry

Urine

Linamarin

HMDB0033699

[98]

Cassava

Observational study

69

Thin-layer chromatography (TLC)

Urine

Linamarin

HMDB0033699

[94]

Cassava (Boiled sweet cassava)

Human meal studies

14

Spectrophotometry

Urine

Linamarin

HMDB0033699

[95]