Dietary factor | Study design | Subjects | Analytical method | Sample type | Discriminating metabolites /Candidate biomarkers | Identifier | Primary reference(s) |
---|---|---|---|---|---|---|---|
Potato | Human meal study | 34 | Radioimmunoassay | Plasma | Solanidine | HMDB0003236 | [27] |
Potato products (i.e., French fries, boiled, baked or mashed potato with or without skin) | Observational study | 57 | Radioimmunoassay | Serum | Solanidine | HMDB0003236 | [28] |
Parallel human dietary study | 2 | ||||||
Unpeeled potato | Parallel human dietary study | 43 | Radioimmunoassay | Serum (1 collection before lunch); Saliva (1 collection, eirher immediately before or after blood sampling) | Solanidine | HMDB0003236 | [104] |
Total potato alkaloids (α-solanine, α-chaconine and aglycone solanidine) | HMDB0003236 HMDB0039353 HMDB0003236 | ||||||
Mashed peeled potatoes | Human meal study | 7 | HPLC | Serum (prior and 0–25 h postdose) | Solanidine | HMDB0003236 | [29] |
α-Solanine | HMDB0034202 | ||||||
α-Chaconine | HMDB0039353 | ||||||
Solution with low glycoalkaloid dose; mashed potato with high glycoalkaloid dose | Human meal study | 14 | HPLC | Serum (prior and 0–96 h postdose) | α-Solanine | HMDB0034202 | [30] |
α-Chaconine | HMDB0039353 | ||||||
Sweet potato (beverage with an extract of anthocyanin) | Human meal study | 6 | liquid chromatography/mass spectrometry (LC/MS) | Plasma and urine (prior and 30–120 min and 24 h postdose) | Pn 3-Caf·sop-5-glc | Not in HMDB | [73] |
Cy 3-Caf·sop-5-glc | Not in HMDB | ||||||
Sweet potato (beverage with an extract of anthocyanin) | Human meal study | 87 | LC-ESI-MS/MS | Urine (2 h postdose) | Pn 3-Caf·sop-5-glc | Not in HMDB | [74] |
Cassava | Observational study | 175 | Spectrophotometry | Urine | Linamarin | HMDB0033699 | [105] |
Cassava (Stiff porridge) | Human meal study | 22 | Spectrophotometry | Urine | Linamarin | HMDB0033699 | [97] |
Cassava (Stiff porridge made from short-soaked roots of bitter cassava varieties) | Observational study | 173 | Spectrophotometry | Urine | Linamarin | HMDB0033699 | [98] |
Cassava | Observational study | 69 | Thin-layer chromatography (TLC) | Urine | Linamarin | HMDB0033699 | [94] |
Cassava (Boiled sweet cassava) | Human meal studies | 14 | Spectrophotometry | Urine | Linamarin | HMDB0033699 | [95] |