Fig. 5

Systemic dietary anti-aging interventions have the potential to also act as inhibitors of age-related diseases. a Current therapeutic approaches target individual diseases that occur in an aged cellular landscape characterized by high concentration of stressors and damaged biomolecules. b The identification of dietary interventions, e.g., specific diets enriched in bioactive natural compounds (or extracts) that either neutralize stressors or trigger a mild activation of cytoprotective mechanisms, will likely increase healthspan suppressing thus the appearance or delaying the onset of most age-related diseases