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Table 2 Association between the FTO-GRS with vitamin B12, folic acid, homocysteine, and obesity traits

From: Evidence for the association between FTO gene variants and vitamin B12 concentrations in an Asian Indian population

Risk alleles n Vitamin B12 (pg/mL) n Homocysteine (μmol/L) n Folic acid (ng/ml) n BMI (kg/m2) n WC (cm) n Odds Ratio (95% CI) of Obesity
0 380 410 ± 202 390 13.2 ± 7.7 390 8.89 ± 5.92 390 26.4 ± 5.0 390 87.6 ± 11.1 194 1.63 (1.07-2.49)
≥ 1 154 356 ± 189 157 14.8 ± 8.9 157 7.89 ± 5.48 157 27.6 ± 5.0 156 90.0 ± 11.6 353
P value 0.018 0.077 0.147 0.009† 0.747 *0.023
  1. Values are given as mean ± standard deviation
  2. P values for differences between 0 and 1 risk alleles were obtained using linear regression model adjusted age, BMI, type 2 diabetes status, type 2 diabetes medication, and sex
  3. P values were obtained by using a general linear model adjusted for age, type 2 diabetes status, type 2 diabetes medication, and sex
  4. *P values were adjusted for age, sex, and type 2 diabetes status using binary logistic regression
  5. Abbreviations: BMI body mass index; WC waist circumference; WHR waist to hip ratio