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Table 6 Effects of protein-enriched milk and isocaloric carbohydrate drink on of IGF-1 and gut peptides

From: Increased protein intake affects pro-opiomelanocortin (POMC) processing, immune function and IGF signaling in peripheral blood mononuclear cells of home-dwelling old subjects using a genome-wide gene expression approach

 

Protein group (n = 14)

Control group (n = 17)

p valueb

Mean (25th–75th )

Mean (25th–75th )

p valuea

Mean (25th–75th )

Mean (25th–75th)

p valuea

Baseline

End of study

Baseline

end of Study

Serum IGF-1 (ng/ml)c

70 (57–81)

75 (62–91)

0.08*

74 (60–87)

73 (64–85)

0.68*

0.07

Plasma GIP (pg/ml)d

136 (79–178)

119 (100–124)

0.51#

125 (94–155)

171 (101–200)

0.10#

0.10

Plasma GLP-1 (pg/ml)d

46 (19–51)

42 (22–45)

0.78#

39 (29–47)

43 (31–49)

0.62#

0.78

Plasma PP (pg/ml)d

287 (150–463)

287 (154–419)

0.55#

225 (153–318)

230 (108–244)

0.33#

0.32

Plasma

Amylin (pg/ml)d

397 (313–461)*

393 (213–509)

0.86#

372 (213–337)

336 (216–351)

0.92#

0.82

Plasma PYY (pg/ml)d

347 (297–400)*

351 (285–440)

0.86#

340 (285–353)

335 (290–376)

0.94#

0.63

  1. aChanges within groups were analyzed using *paired sample t test and #Wilcoxon signed-ranks test. bChanges between groups were analyzed using cindependent sample t test and dWilcoxon-Mann-Whitney test. *n = 13